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首页> 外文期刊>Brazilian Journal of Medical and Biological Research >Tissue fusion technology versus suture and staple in porcine bowel anastomosis: an in vivo study
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Tissue fusion technology versus suture and staple in porcine bowel anastomosis: an in vivo study

机译：组织融合技术与苏碱肠吻合术中的缝合和主食：体内研究

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The aim of this study was to make a comparison between the tissue fusion technique and conventional methods for sealing bowel anastomosis. Eighteen female domestic pigs (Suidae, Sus) were used in our study. Tissue-fused anastomoses (LigaSure groups) were made in 13 animals (5 anastomoses per animal), which were subdivided into 4 groups according to different manufacturing settings: “LigaSure-L-1” and “LigaSure-L-2”, with low energy output level with 1 or 2 device-activated tissue sealing times, and “LigaSure-M” and “LigaSure-H”, with medium or high energy output level. As controls, automatically stapled (GIA group) and hand-sewn (suture group) anastomoses were utilized in 3 and 2 animals, respectively. There was no statistical difference in the overall leakage rate between the GIA group (6.7%) and the LigaSure groups (15%) (P=1.000). There was less proliferating epithelium covering the anastomosis gap in the LigaSure groups compared with the other two groups. The gap between the two extremities of muscular layers of the anastomosis in the LigaSure groups was filled with collagen fibers. More proliferating cell nuclear antigen (PCNA)-positive cells were found in the anastomoses of the LigaSure groups compared with the other two groups (P=0.010). Our results showed that the tissue fusion technology was a feasible and safe method for anastomoses.
机译：本研究的目的是在组织融合技术与常规方法之间进行比较，用于密封肠吻合术。我们的研究中使用了十八雌性猪（Suidae，Sus）。组织稠合的吻合术（LIGASURE组）在13只动物（每只动物5吻合）中制成，根据不同的制造环境细分为4组：“LIGASURE-L-1”和“LIGASURE-L-2”，具有低能量输出水平具有1或2个器件激活的组织密封时间，以及“LIGASURE-M”和“LIGASURE-H”，具有中等或高能量输出水平。作为对照，分别在3和2只动物中使用自动烘烤（GIA组）和手工缝制（缝合组）吻合术。 GIA组（6.7％）和LIGASURE组（15％）之间的总泄漏率没有统计学差异（15％）（P = 1.000）。与其他两组相比，覆盖了覆盖了降解组中的吻合术的增殖上皮。在胶原纤维中充满了胶原纤维的吻合术中吻合术的两个肢体之间的间隙。与其他两组相比，在LIGASURE组的吻合中发现更多增殖细胞核抗原（PCNA） - 阳性细胞（P = 0.010）。我们的研究结果表明，组织融合技术是一种可行和安全的吻合方法。

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