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首页> 外文期刊>BMC Pregnancy and Childbirth >Successful monozygotic triplet pregnancy after a single blastocyst transfer following in vitro maturation of oocytes from a woman with polycystic ovary syndrome: a case report
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Successful monozygotic triplet pregnancy after a single blastocyst transfer following in vitro maturation of oocytes from a woman with polycystic ovary syndrome: a case report

机译：在来自多囊卵巢综合征的女性的卵母细胞的体外成熟后，单一囊肿三重胶质妊娠在卵母细胞的体外成熟后：案例报告

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BACKGROUND:Although women with polycystic ovarian syndrome (PCOS)-related sub-fertility are high responders to controlled ovarian stimulation, it is difficult to obtain mature oocytes in these women. Therefore, in vitro maturation (IVM), which is the technique of letting the contents of the ovarian follicles and the oocytes inside mature in vitro, has often been proposed in such women. We describe the first successful delivery of monozygotic triplets resulting from transfer of a single blastocyst following IVM of oocytes.CASE PRESENTATION:A 32-year-old nulligravida female with PCOS underwent IVM. She underwent vitrified-warmed single blastocyst transfer following IVM, and a dichorionic triamniotic triplet pregnancy was confirmed at 8?weeks. Healthy triplets were delivered by cesarean section at 33?weeks' gestation. This is the first case of monozygotic triplets derived from IVM oocytes that were successfully delivered. The determination of chorionicity and amnionicity is generally supposed until 3?days after fertilization, and no division or splitting of her embryo was observed on transfer. Interestingly, her embryo might have split after the transfer, resulting in a dichorionic triamniotic triplet pregnancy.CONCLUSIONS:Patients should be informed of a possible increased risk of monozygotic multiple pregnancies after single embryo transfer following IVM.
机译：背景：虽然具有多囊卵巢综合征（PCOS）的女性 - 相关的副肥力是受控卵巢刺激的高响应者，但很难在这些女性中获得成熟的卵母细胞。因此，在这些女性中通常提出了在体外成熟（IVM），这是使卵巢卵泡的内容物和体外成熟内部成熟的卵母细胞的技术。我们描述了由oocytes.case演示文稿的IVM次数转移的单一囊肿的首次成功递送单一血栓摸摸地段，这是一个卵母细胞介绍中的一个胚泡：一名32岁的无硫穿的女性，PCOS接受了IVM。她经历了IVM之后玻璃化温度的单胚性转移，并且在8℃确认了一定的二核龙氏菌三胞胎妊娠。健康的三胞胎由剖宫产，33个月的妊娠。这是衍生自成功递送的IVM卵母细胞的单一程度三胞胎的第一种情况。抑制性和氨基因度的测定通常在受精后3-3-天施用，并且在转移时没有观察到她的胚胎的分裂或分裂。有趣的是，她的胚胎可能会在转移后分裂，导致暗中枝胞胎三胞胎妊娠。结论：在IVM后单胚胎转移后，应了解患者的单一性多重妊娠风险。

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