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首页> 外文期刊>BMC Psychiatry >Depression, anxiety, and associated factors in patients with diabetes: evidence from the anxiety, depression, and personality traits in diabetes mellitus (ADAPT-DM) study
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Depression, anxiety, and associated factors in patients with diabetes: evidence from the anxiety, depression, and personality traits in diabetes mellitus (ADAPT-DM) study

机译：糖尿病患者的抑郁症，焦虑和相关因素：糖尿病患者焦虑，抑郁和人格特征的证据（适应DM）研究

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Depression and anxiety are common psychiatric complications affecting patients with diabetes mellitus. However, data on the prevalence of depression, anxiety, and associated factors among Malaysian diabetic patients is scarce. The Anxiety, Depression, and Personality Traits in Diabetes Mellitus (ADAPT-DM) study aimed to determine the prevalence of depression and anxiety, and their associated factors in the Malaysian diabetic population. This cross-sectional study recruited 300 diabetic patients via convenience sampling from the Endocrine outpatient clinic of Universiti Kebangsaan Malaysia Medical Centre, a tertiary referral healthcare facility in Kuala Lumpur. Socio-demographic characteristics and clinical history were obtained from each participant. The Generalised Anxiety Disorder-7 (GAD-7) was administered to assess anxiety symptoms, the Beck Depression Inventory (BDI) to assess depressive symptoms, the Big Five Inventory (BFI) to evaluate personality traits, and the World Health Organization Quality of Life-BREF (WHOQOL-BREF) to measure quality of life (QOL). Stepwise multiple logistic regression analyses were performed to determine the association between various factors, and depression and anxiety. The prevalence of depression was 20% (n?=?60) while anxiety was 9% (n?=?27). Co-morbid depression (adjusted odds ratio [OR]?=?9.89, 95% confidence interval [CI]?=?2.63–37.14, p?=?0.001) and neuroticism (adjusted OR?=?11.66, 95% CI?=?2.69–50.47, p?=?0.001) increased the odds of developing anxiety, while conscientiousness (adjusted OR?=?0.45, 95% CI?=?0.23–0.80, p?=?0.004) and greater psychological-related QOL (adjusted OR?=?0.47, 95% CI?=?0.29–0.75, p?=?0.002) were protective. Co-morbid anxiety (adjusted OR?=?19.83, 95% CI?=?5.63–69.92, p???0.001) increased the odds of depression, while older age (adjusted OR?=?0.96, 95% CI?=?0.93–0.98, p?=?0.002), social relationship-related QOL (adjusted OR?=?0.84, 95% CI?=?0.71–.0.99, p?=?0.047), and physical health-related QOL (adjusted OR?=?0.69, 95% CI?=?0.58–0.83, p???0.001) were protective. The study findings signify the need to screen for co-morbid depression and anxiety, as well as personality traits and QOL, and to include psychosocial interventions when planning a multidisciplinary approach to managing diabetes.
机译：抑郁和焦虑是影响糖尿病患者的常见精神疾病。然而，关于抑郁症，焦虑和相关因素的患病率的数据稀缺。糖尿病（Adap-DM）研究中的焦虑，抑郁和人格特征旨在确定抑郁和焦虑的患病率，以及马来西亚糖尿病群的相关因素。这种横断面研究通过kuala lumpur大学凯班达安马来西亚医疗中心的内分泌门诊诊所的便利患者招募了300名糖尿病患者。每个参与者都可以获得社会人口统计学特征和临床历史。给予广泛的焦虑症-7（GAD-7）进行评估焦虑症状，贝克抑郁症库存（BDI）评估抑郁症状，大五库存（BFI）评估人格特质，以及世界卫生组织的生活质量-bref（whoqol-bref）测量生活质量（qol）。进行逐步进行多元逻辑回归分析以确定各种因素和抑郁和焦虑之间的关联。抑郁症的患病率为20％（n？=？60），而焦虑是9％（n？=？27）。共同病态抑郁症（调整赔率比[或]？=？9.89,95％置信区间[CI]？=？2.63-37.14，P？= 0.001）和神经质（调节或？=？11.66,95％CI？ =？2.69-50.47，p？= 0.001）增加了发展焦虑的几率，而休闲性（调整或？=？0.45,95％CI？=？0.23-0.80，P？=？0.004）和更大的心理学相关QoL（调整或α=？0.47,95％CI？=？0.29-0.75，p？= 0.002）是保护的。共同焦虑（调整或？= 19.83,95％CI？=？5.63-69.92，p？

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