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首页> 外文期刊>Clinical ophthalmology >Comparison of intraocular pressure fluctuations before and after ab interno trabeculectomy in pseudoexfoliation glaucoma patients
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Comparison of intraocular pressure fluctuations before and after ab interno trabeculectomy in pseudoexfoliation glaucoma patients

机译：伪萃取青光眼患者AB间Trabeculectomy前后的眼压波动比较

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Purpose: Ab interno trabeculectomy (AIT) with the Trabectome has been shown to reduce intraocular pressure (IOP) in eyes with pseudoexfoliation (PEX) glaucoma. Here, we examined the change of IOP fluctuations before and after only AIT or AIT with cataract surgery in PEX patients using the contact lens sensor Triggerfish?. Methods: This was a prospective open-label study. Twenty-four consecutive patients with PEX glaucoma were included. Twelve patients underwent cataract surgery and AIT (triple-surgery group), and 12 patients underwent only AIT (single-surgery group). In each eye, IOP fluctuations over 24 h were measured with the contact lens sensor before and at 3 months after the surgery. We compared the change of IOP fluctuation before and after operation. We also evaluated the difference in IOP changes between the triple- and single-surgery groups. Results: At 3 months after the surgeries, the mean IOP was significantly reduced from 23.5±6.5 mmHg to 14.6±2.8 mmHg in the single-surgery group and from 22.5±3.0 mmHg to 11.5±2.9 mmHg in the triple-surgery group. The mean IOP reduction rate was significantly higher in the triple-surgery group compared to the single-surgery group ( p =0.0358). In both groups, the mean range of IOP fluctuations was significantly decreased during nocturnal periods. The mean range of 24 h IOP fluctuations was decreased in the triple-surgery group ( p =0.00425), not in the single-surgery group ( p =0.970). Conclusion: Triple surgery could decrease IOP value and the IOP fluctuations to a greater extent than single surgery in PEX glaucoma patients.
机译：目的：已经显示出与捕获术中的与捕获组的间隙细胞切除术（AIT）减少眼睛中的眼压（IOP）与伪萃取物（PEX）青光眼。在这里，我们在使用隐形眼镜传感器引发物 的Pex患者中，在PEX患者中只有AIT或AIT的AIT手术之前和AIT的变化。方法：这是一项潜在的开放标签研究。包括二十四名患有Pex青光眼的患者。 12名患者接受了白内障手术和AIT（三重手术组），12名患者只接受AIT（单手术组）。在每只眼睛中，在手术后3个月之前和3个月之前测量超过24小时的IOP波动。我们比较了手术前后的IOP波动的变化。我们还评估了三重和单手术组之间的IOP变化的差异。结果：在手术后3个月，单手术组中的平均IOP显着降低至14.6±2.8mmHg至14.6±2.8mmHg，在三重手术组中为22.5±3.0mmHg至11.5±2.9 mmHg。与单手术组相比，三重手术组的平均IOP降低率明显高（P = 0.0358）。在这两组中，夜间时期的IOP波动的平均范围显着降低。在三重手术组（P = 0.00425）中，24小时触觉波动的平均范围减少（P = 0.00425），而不是单手术组（P = 0.970）。结论：三重手术可以在更大程度上降低IOP值和IOP波动，而不是PEX青光眼患者的单手术。

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