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Idiopathic retinal vasculitis, aneurysms, and neuroretinitis (IRVAN) syndrome: clinical perspectives

机译：特发性视网膜血管炎，动脉瘤和神经尿素炎（IRVAN）综合征：临床观点

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摘要

Idiopathic retinal vasculitis, aneurysms, and neuroretinitis (IRVAN) syndrome typically affects young, healthy individuals. Despite the dramatic fundus appearance seen in this syndrome, these patients are usually asymptomatic. The syndrome includes peculiar vascular abnormalities in the form of multiple aneurysmal dilatations seen along retinal arterioles and optic nerve-head arterioles, which are best appreciated on fluorescein angiography. Neuroretinitis and retinal vasculitis are seen in all patients, and manifested by staining of the optic nerve head and diffuse leakage from vessels, mainly arterioles, on fluorescein angiography. The devastating vision-threatening outcomes of this syndrome include exudative retinopathy and extensive peripheral retinal nonperfusion areas, which can eventually lead to neovascularization. This review summarizes current knowledge on the variable clinical aspects of this disease, highlighting diagnostic and treatment strategies.
机译：特发性视网膜血管炎，动脉瘤和神经遗传炎（Irvan）综合征通常影响年轻，健康的个体。尽管在该综合症中看到了戏剧性的眼底外观，但这些患者通常是无症状的。该综合征包括沿视网膜动脉瘤和视神经头动脉瘤的多种动脉瘤扩张形式的特殊血管异常，这对荧光素血管造影最受欢迎。在所有患者中都可以看到神经尿素炎和视网膜血管炎，并通过在荧光素血管造影上染色视神经头部并从容器中漫射泄漏，主要是动脉瘤。该综合征的毁灭性视力威胁结果包括渗出性视网膜病变和广泛的外周视网膜非灌症区，最终可能导致新血管形成。本综述总结了目前关于该疾病的可变临床方面的知识，突出了诊断和治疗策略。

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