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Effect of nanoliposomes on the stabilization of incorporated retinol

机译:纳米素体对掺入视黄醇稳定的影响

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Nanoliposomes containing retinol were prepared, and the stability of the incorporated retinol was evaluated. Average particle size of nanoliposomes was 98 nm. Retinol was readily incorporated into nanoliposomes with incorporation efficiencies higher than 99%. The bare retinol in the buffer was almost degraded within 2 days of storage, while at least, over 20% of the initial retinol in nanoliposomes was kept until 8 days in all experimental conditions tested. The incorporated retinol in nanoliposomes was more rapidly degraded as temperature increases under both dark and UV light condition during the whole period of storage, and UV light slightly decreased the stability of retinol in nanoliposomes.
机译:制备含有视黄醇的纳米脂质体,评价掺入的视黄醇的稳定性。纳米脂质体的平均粒度为98nm。将视黄醇容易地掺入纳米脂质体中,掺入效率高于99%。缓冲液中的裸露视黄醇几乎在储存的2天内降解,而至少在测试的所有实验条件下保持纳米脂质体中的超过20%的初始视黄醇。纳米脂质体中的掺入式视黄醇更快地降解,因为在整个储存期间的暗和UV光条件下温度升高,并且UV光略微降低了纳米体中视黄醇的稳定性。

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