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首页> 外文期刊>International Journal of Environmental Research and Public Health >Validation and Adaptation of the “Modified Transplant Symptom Occurrence and Symptom Distress Scale” for Kidney Transplant Recipients
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Validation and Adaptation of the “Modified Transplant Symptom Occurrence and Symptom Distress Scale” for Kidney Transplant Recipients

机译：肾移植受者“改性移植症状发生和症状遇险量表”的验证和调整

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The aim was to adapt and validate the Modified Transplant Symptom Occurrence and Symptom Distress Scale (MTSOSD-59R) for kidney transplant recipients undergoing immunosuppressive therapy in Korea. The MTSOSD-59R has been used with solid organ transplant recipients globally to assess the adverse effects of immunosuppressive medication. A descriptive cross-sectional design was used. MTSOSD-59R was first translated, and pilot tested. Next, content validity was established with nine organ transplant experts. Then, from October 2017 to October 2018, the Korean MTOSOSD-59R was administered to a convenience sample of 122 kidney transplant recipients recruited from a single center. Ridit analysis was used to measure symptom occurrence and distress. The known-group approach was used to test the construct validity using Mann–Whitney U tests for between-group comparisons. The content validity index for MTSOSD-59R was 0.98, and known-group validity was confirmed. The split-half Spearman–Brown corrected reliability coefficient was 0.902 for symptom occurrence and 0.893 for symptom distress. The four most frequent and distressing symptoms were fatigue, lack of energy, thinning hair, and erectile dysfunction (male). Results suggest this Korean MTSOSD-59R adaptation has adequate language, construct validity, and reliability to gather meaningful information from kidney transplant recipients in Korea.
机译：目的是适应和验证治疗韩国免疫抑制治疗的肾移植受试者的改良移植症状发生和症状遇险量表（MTSOSD-59R）。 MTSOSD-59R已被全球与固体器官移植受体一起使用，以评估免疫抑制药物的不利影响。使用描述性横截面设计。 MTSOSD-59R首次翻译，并测试了先导。接下来，用九个器官移植专家建立内容有效性。然后，从2017年10月到2018年10月，韩国MTOSOSD-59R被施用到从单一中心招募的122个肾移植受者的便利样本。 Ridit分析用于测量症状发生和痛苦。已知的群体方法用于使用Mann-Whitney U测试来测试构建有效性，用于组间比较。 MTSOSD-59R的内容有效性指数为0.98，确认已知的综合有效性。症状发生的症状发生和0.893的症状遇险为0.902，分裂半刺型校正可靠性系数为0.902。四种最常见和令人痛苦的症状是疲劳，缺乏能量，稀释的头发和勃起功能障碍（男性）。结果表明，此韩国MTSOSD-59R适应具有足够的语言，构建有效性和可靠性，以收集韩国肾移植受者的有意义信息。

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