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首页> 外文期刊>International Journal of Research in Medical Sciences >Association of chronic viral hepatitis with ABO blood groups and rhesus (Rh) factor
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Association of chronic viral hepatitis with ABO blood groups and rhesus (Rh) factor

机译：慢性病毒性肝炎与ABO血液组和恒河（RH）因子

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Background: Chronic viral hepatitis includes hepatitis B and hepatitis C and is responsible for causing the deaths of millions of people all across the world each year. Although there are small studies in literature about association between ABO blood groups and chronic viral hepatitis, only few studies found relation between them. The objective of this case control study is to establish a relation between the host factors and these viral infections. Methods: This is a case control study on patients diagnosed with CVHB and CVHC. The study was conducted on 508 patients reported to Nishtar Hospital, Multan and Sheikh Zayd Hospital, Rahim Yar Khan, Pakistan.709 healthy blood donors were selected as a control group from Nishtar Hospital blood bank during December 2016 and December 2017.The results were subjected to SPSS v.20 for analysis using the chi square test. The patients and blood donors were also asked about certain demographic factors like age, sex and blood transfusions. Results: Among CVHB patients,173(100%), the distribution of blood groups was following: Group A, 38 (21.96%), B, 57 (32.94%), AB, 11 (6.35%), O, 67 (38.72%). 158 (91.32%) were Rh positive and 15 (8.67%) Rh negative. In CVHC patients, 335 (100%), the distribution was following: Group A, 69 (20.59%), B, 123 (36.71%), AB, 24 (7.16%), O, 119 (35.52%). 303 (90.44%) were Rh positive while 32 (9.55%) were Rh negative. In healthy blood donors, 167 (23.55%) were group A, 225 (31.73%) group B, 41(5.78%) group AB, 276 (38.92%) group O.632 (89.13%) were Rh positive and 77 (10.86%) Rh negative. Conclusions: There was no significant difference between blood groups(p>0.5) and Rh(p>0.5) with chronic viral hepatitis. However, it was also observed that the infections of HCV increase among (26-45) years old patients while the HBV infections increase with progression of age. Association of chronic viral hepatitis infection with blood group types needs more studies to get more knowledge about this aspect.
机译：背景：慢性病毒性肝炎包括乙型肝炎和丙型肝炎，并负责每年在全球各地的数百万人死亡。虽然有关于ABO血型和慢性病毒性肝炎之间关联的文学研究，但在它们之间只有很少的研究。本案例控制研究的目的是建立宿主因子与这些病毒感染之间的关系。方法：这是对诊断患有CVHB和CVHC的患者的病例对照研究。该研究进行了508名患者向Nishtar医院，Mushtar Houst Hospital，Rahim Yar Khan，巴基斯坦，巴基斯坦，Pakistan.709健康献血者被选为2016年12月和2017年12月的Nishtar医院血库的对照组。结果受到了影响使用Chi Square测试来分析SPSS V.20。患者和献血者也被问及某些人口统计因素，如年龄，性别和输血等。结果：在CVHB患者中，173名（100％），血液分布如下：A，38（21.96％），B，57（32.94％），AB，11（6.35％），O，67（38.72） ％）。 158（91.32％）是RH阳性，15（8.67％）RH阴性。在CVHC患者中，335（100％），分布如下：A，69（20.59％），B，123（36.71％），AB，24（7.16％），O，119（35.52％）。 303（90.44％）是RH阳性，而32（9.55％）是RH阴性的。在健康的血液供体中，167（23.55％）是A，225（31.73％）B组，41（5.78％）AB，276（38.92％）组O.632（89.13％）是RH阳性和77（10.86 ％）Rh阴性。结论：血液组（P> 0.5）和RH（P> 0.5）与慢性病毒性肝炎无显着差异。然而，还观察到，在（26-45）岁患者中，HCV的感染增加，而HBV感染随着年龄的进展而增加。慢性病毒性肝炎感染与血型类型的关联需要更多的研究以获得更多关于这方面的知识。

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