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Chronic viral hepatitis and their relation to ABO blood groups and rhesus (Rh) factor

机译：慢性病毒性肝炎及其与ABO血型和恒河猴（Rh）因子的关系

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ABO blood groups have shown some association with various diseases. Although there are small studies in literature about association between ABO blood groups and chronic viral hepatitis, only few studies found relation between fibrosis severity in chronic viral hepatitis C (CVHC) and ABO blood groups. The aim of this survey is to determine the frequency of different blood groups and Rh (Rhesus) factor in chronic viral hepatitis B (CVHB) and C, to find out if such a host factor may play a role in trend of these viral infections. This is a case control study on patients with CVHB and CVHC referring to infectious diseases research center, Isfahan, Iran and healthy blood donors (HBDs) referring to Isfahan blood bank were selected as control during April 2003 and April 2007. 170 cases with chronic viral hepatitis (130 CVHB and 40 CVHC) and 680 cases of healthy blood donor enrolled in this study. Statistical analyses were performed using SPSS v. 11.0.1 using c2test. Distribution of blood groups and Rh in CVHB were as the following: Group A, 42 (32.3%), B, 30 (23.1%), AB, 10 (7.7%), O, 48 (36.9%). 115 (88.46%) were Rh positive and 15 cases (11.54%) Rh negative. In CVHC 10 (25%) cases were blood group A, B 14 (35%) cases group B another 14 (35%) case were AB and 2 cases (5%) group B, out of them 37 (92.5%) were Rh positive and remaining 3 (7.5%) were Rh negative. In healthy blood donors 212 (31%) were group A,183 group B (26.8%), 66 group AB(9.7%) and 222 (32.5%) group B. Positive Rh found in 611 individuals (89.45%) and Rh negative 72 (10.55%). Comparing relative frequency of ABO blood groups and Rh between cases of chronic viral hepatitis and control blood donors, there was no significant difference between blood groups (p > 0.5) or Rh (p > 0.5) with chronic viral hepatitis.
机译：ABO血型已显示出与各种疾病的某种关联。尽管有关ABO血型与慢性病毒性肝炎之间关系的文献研究很少，但只有极少的研究发现慢性C型肝炎（CVHC）纤维化严重程度与ABO血型之间存在关联。这项调查的目的是确定慢性乙型肝炎病毒（CVHB）和丙型肝炎病毒中不同血型和Rh（Rhesus）因子的频率，以查明这种宿主因子是否可能在这些病毒感染的趋势中起作用。这是一项针对病例的对照研究，分别针对伊朗伊斯法罕传染病研究中心的CVHB和CVHC患者以及伊朗伊斯法罕血库的健康献血者（HBD），分别于2003年4月和2007年4月进行控制。170例慢性病毒性肝炎患者这项研究包括肝炎（130 CVHB和40 CVHC）和680例健康献血者。使用c2test使用SPSS v.0.1.1执行统计分析。 CVHB中血型和Rh的分布如下：A组，42（32.3％），B，30（23.1％），AB，10（7.7％），O，48（36.9％）。 Rh阳性115例（88.46％），Rh阴性15例（11.54％）。在CVHC中，A组为10（25％），B组为14（35％），AB组为14（35％），B组为2例（5％），其中B组为37（92.5％）。 Rh阳性，其余3个（7.5％）为Rh阴性。在健康献血者中，A组为212（31％），B组为（183.6％），AB组为66（9.7％），B组为222（32.5％）。Rh阳性的有611人（89.45％），Rh为阳性负72（10.55％）。比较慢性病毒性肝炎病例和对照组献血者之间的ABO血型和Rh相对频率，在慢性病毒性肝炎的血型（p> 0.5）或Rh（p> 0.5）之间没有显着差异。

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