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New oral anticoagulants: key messages for clinicians

机译:新的口腔抗凝血剂:临床医生的关键信息

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New oral anticoagulants are an effective and safe alternative to vitamin K antagonists in many fields of clinical practice. The use of the direct inhibitors of activated Factor II (dabigatran) and activated Factor X (apixaban and rivaroxaban), both in patients with non-valvular atrial fibrillation (NVAF) and those with acute venous thromboembolism (VTE), is of great interest for internal medicine physicians. This paper aims to give practical guidance on management (starting therapy, follow up and bleeding complications) of patients treated with dabigatran, rivaroxaban or apixaban for NVAF or acute VTE providing practical tables concerning the phases of therapy, management of complications, drug interaction and dose adjustment if renal impairment occurs.
机译:新的口腔抗凝血剂是在许多临床实践领域的维生素K拮抗剂是一种有效和安全的替代品。在非瓣膜心房颤动(NVAF)和急性静脉血栓栓塞(VTE)的患者中,使用活性因子II(Dabigatran)和活性因子X(Apixaban和Rivaroxaban)的直接抑制剂的用途对内科医生。本文旨在为NVAF,Rivaroxaban或Apixaban治疗的患者提供实际指导(开始治疗,后续和出血并发症),用于NVAF或急性VTE提供关于治疗阶段,并发症管理,药物相互作用和剂量的实用表如果发生肾脏损害,调整。

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