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首页> 外文期刊>Endoscopy International Open >EDGE in Roux-en-Y gastric bypass: How does it compare to laparoscopy-assisted and balloon enteroscopy ERCP: a systematic review and meta-analysis
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EDGE in Roux-en-Y gastric bypass: How does it compare to laparoscopy-assisted and balloon enteroscopy ERCP: a systematic review and meta-analysis

机译：Roux-Zh-Y胃旁路的边缘：它与腹腔镜辅助和气球肠镜肠镜ERCP进行比较：系统评价和荟萃分析

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Background and study aims?Endoscopic ultrasound-directed transgastric ERCP (EDGE) is a new endoscopic procedure to perform ERCP in Roux-en-y gastric bypass (RYGB) patients. The aim of this study was to conduct a systematic review and meta-analysis to evaluate technical success, clinical success and adverse effects of EDGE and compare it to laparoscopic ERCP (LA-ERCP) and balloon ERCP (BE-ERCP). Patients and methods?We conducted a comprehensive search of several databases and conference proceedings including PubMed, EMBASE, Google-Scholar, LILACS, SCOPUS, and Web of Science databases to identify studies reporting on EDGE, LA-ERCP, and BE-ERCP. The primary outcome was to evaluate technical and clinical success of all three procedures and the secondary analysis focused on calculating the pooled rate of all adverse events (AEs), along with the commonly reported AE subtypes. Results?Twenty-four studies on 1268 patients were included in our analysis with the majority of the population being males with mean age 53.72 years. Pooled rates of technical and clinical success with EDGE wer 95.5?% and 95.9?%, with LA-ERCP were 95.3?% and 92.9?% and were BE-ERCP were 71.4?% and 58.7?%, respectively. Pooled rates of all AEs with EDGE were 21.9?%, with LA-ERCP 17.4?% and with BE-ERCP 8.4?%. Stent migration was the most common AE with EDGE with 13.3?% followed by bleeding with 6.6?%. Conclusion?Our meta-analysis demonstrated that the technical and clinical success of EDGE procedure is better than BE-ERCP and comparable to that of LA-ERCP in RYGB patients. EDGE also has a similar safety profile as compared to LA-ERCP but has higher AE rate as compared to BE-ERCP.
机译：背景和研究目标？内窥镜超声波定向的综合ERCP（边缘）是在Roux-Zh-Y胃旁路（RYGB）患者中进行ERCP的新内窥镜程序。本研究的目的是进行系统审查和荟萃分析，以评估技术成功，临床成功和边缘的不利影响，并将其与腹腔镜ERCP（LA-ERCP）和气球ERCP（BE-ERCP）进行比较。患者和方法？我们对几个数据库和会议程序进行了全面搜索，包括PubMed，Embase，Google-Scholar，Lilacs，Scopus和科学数据库网络，以识别Edge，La-ERCP和BE-ERCP的研究报告。主要结果是评估所有三种程序的技术和临床成功，并侧重分析集中于计算所有不良事件（AES）的合并率以及常见的AE亚型。结果？在我们的分析中纳入了1268名患者的二十四项研究，其中大多数人口为53.72岁的男性。利用边缘汇集的技术和临床成功的汇率95.5？％和95.9？％，La-ERCP分别为95.3〜92.9〜92.9℃，分别为71.4〜％和58.7倍。所有AES的汇总率为21.9？％，带有LA-ERCP 17.4？％，BE-ERCP 8.4？％。支架迁移是最常见的ae，边缘为13.3〜％，然后用6.6℃渗出。结论？我们的荟萃分析表明，边缘程序的技术和临床成功优于ERCP，并与RYGB患者的LA-ERCP相当。与La-ERCP相比，边缘也具有类似的安全性，但与BE-ERCP相比具有更高的AE速率。

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