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首页> 外文期刊>Endoscopy International Open >Outcomes of endoscopic sleeve gastroplasty; how does it compare to laparoscopic sleeve gastrectomy? A systematic review and meta-analysis
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Outcomes of endoscopic sleeve gastroplasty; how does it compare to laparoscopic sleeve gastrectomy? A systematic review and meta-analysis

机译：内窥镜袖腹膜术的结果;它是如何与腹腔镜套胃切除术进行比较？系统审查和荟萃分析

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Background and study aims?Endoscopic sleeve gastroplasty (ESG) is a novel moderately invasive technique in endo-bariatrics as compared to laparoscopic sleeve gastrectomy (LSG). Data is limited as to its efficacy and safety. Methods?We searched multiple databases from inception through August 2019 to identify studies that reported on ESG in the treatment of obesity. Our goals were to calculate the pooled rates of total weight loss (%TWL), excess weight loss (%EWL), and body mass index (BMI) at 1 month, 6 months, and 12 months with ESG. We included studies that reported on LSG, in a similar time frame as ESG, and compared the 12-month outcomes. Results?From eight studies on ESG (1815 patients), the pooled rates of %TWL at 1 month, 6 months, and 12 months were 8.7 (7.2–10.2), 15.3 (14.1–16.6) and 17.1 (15.1–19.1), respectively. The pooled rates of %EWL at 1 month, 6 months, and 12 months were 31.7 (29.3–34.1), 59.4 (57–61.8) and 63 (51.3–74.6), respectively. The pooled rates of BMI at 1?m, 6?m, and 12?m were 32.6 (31–34.3), 30.4 (29–31.8) and 30 (27.7–32.3, Isup2/sup?=?97), respectively. At 12 months, the pooled %TWL, %EWL and BMI with LSG (7 studies, 2179 patients) were 30.5 (27.4–33.5), 69.3 (60.1–78.4) and 29.3 (27.1–31.4) respectively. On comparison analysis, %TWL with LSG was superior to ESG (P?=?0.001). %EWL and BMI were comparable. All adverse events, bleeding and gastro-esophageal reflux disease were significantly lower with ESG when compared to LSG. Conclusion?ESG demonstrates acceptable weight loss parameters and seems to have a better safety profile when compared to LSG.
机译：背景和研究旨在？内窥镜套筒腹膜成形术（ESG）是与腹腔镜套管胃切除术（LSG）相比，内窦腹膜腹膜腹部新型侵入性技术。数据受到其疗效和安全性的限制。方法？我们于2019年8月搜索了从成立的多个数据库，以确定在肥胖治疗ESG上报告的研究。我们的目标是在1个月，6个月和12个月内计算总体重减轻（％TWL），过量减肥（％EWL）和体重指数（BMI）的汇总率。我们包括在LSG上报告的研究，在类似的时间范围内作为ESG，并比较了12个月的结果。结果？从ESG（1815名患者）的八项研究中，1个月，6个月和12个月的汇总率为1,87（7.2-10.2），15.3（14.1-16.6）和17.1（15.1-19.1），分别。 1个月，6个月和12个月的％EWL的汇总率分别为31.7（29.3-34.1），59.4（57-61.8）和63（51.3-74.6）。 BMI的汇集速率为1？M，6？m和12？m为32.6（31-34.3），30.4（29-31.8）和30（27.7-32.3，I 2 ？= ？97）分别。 12个月，汇集％TWL，％EWL和BMI与LSG（7项研究，2179名患者）分别为30.5（27.4-33.5），69.3（60.1-78.4）和29.3（27.1-31.4）。在比较分析时，具有LSG的％TWL优于ESG（P？= 0.001）。 ％EWL和BMI是可比的。与LSG相比，ESG，所有不良事件，出血和胃食管反流疾病显着降低。结论？ESG展示了可接受的减肥参数，并且与LSG相比，似乎具有更好的安全性。

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