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Use of adrenaline continuous infusion to treat hypotension during general anaesthesia in a cow and a calf

机译:使用肾上腺素连续输注治疗牛和小牛的全身麻醉期间的低血压

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Hypotension is one of the most common complications observed during inhalation anaesthesia in veterinary patients. Treatment of hypotension in cattle is more challenging than in other species, owing to the limited number of drugs licensed in food producing animals. The use of adrenaline as an infusion to support blood pressure has not been described previously in bovines. A cow and a calf presented to University College Dublin Veterinary Hospital for bilateral mandibular fracture repair and bladder rupture repair respectively, developed severe anaesthetic related hypotension unresponsive to conventional treatments. In both cases an adrenaline infusion was started and slowly increased to effect, with infusion rates ranging from 0.01 to 0.25?μg/kg/min. Blood pressure increased as the adrenaline infusion rate increased, but clinically significant improvements in blood pressure were only observed with infusion rates exceeding 0.05?μg/kg/min. The side effect observed with adrenaline infusion was an increase in plasma lactate levels in both cases. Both animals were euthanised due to non-anaesthetic related complications. Maintenance of normotension is important during bovine anaesthesia to prevent the development of post-anaesthetic complications. In the cases described here, adrenaline was effective as an additional treatment of anaesthetic related hypotension. Further research is required to establish the recommended infusion rates, cardiovascular effects and possible side effects of adrenaline infusion administration as a treatment for hypotension in bovines.
机译:低血压是兽医患者吸入麻醉期间观察到最常见的并发症之一。由于在食品生产动物中许可的药物数量有限,对牛的低血压治疗比其他物种更具挑战性。在牛肠中尚未描述使用肾上腺素作为抑制以支持血压的输注。一头母牛和小牛展示了大学学院都柏林兽医医院,分别为双侧下颌骨折修复和膀胱破裂修复,显得严重的麻醉相关的低血压对常规治疗。在这两种情况下,肾上腺素输注开始并缓慢增加以效果,输注速率范围为0.01至0.25≤μg/ kg / min。随着肾上腺素输注速率的增加,血压增加,但血压临床显着改善仅被输液率超过0.05Ω·μg/ kg / min。用肾上腺素输注观察到的副作用是两种情况下血浆乳酸水平的增加。由于非麻醉相关并发症,两只动物都被安乐死。在牛麻醉期间,常压的维持是重要的,以防止发出麻醉后并发症。在这里描述的病例中,肾上腺素是有效的,作为麻醉相关的低血压的额外治疗。需要进一步的研究来建立肾上腺素输注给药的推荐输液率,心血管效应和可能的副作用作为牛粪中的低血压治疗。

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