...
  • 主题
高级搜索  >
历史搜索 清空历史
首页> 外文期刊>European Journal of Dentistry >Evaluation of Efficacy of Coenzyme Q10 as an Adjunct to Nonsurgical Periodontal Therapy and Its Effect on Crevicular Superoxide Dismutase in Patients with Chronic Periodontitis
【24h】

Evaluation of Efficacy of Coenzyme Q10 as an Adjunct to Nonsurgical Periodontal Therapy and Its Effect on Crevicular Superoxide Dismutase in Patients with Chronic Periodontitis

机译：辅酶Q10疗效评价作为非牙科牙周治疗辅助辅助疗效的疗效及其对慢性牙周炎患者粘沟超氧化物歧化酶的影响

获取原文
           
页面导航
  • 摘要
  • 著录项
  • 相似文献
  • 相关主题

摘要

Objectives?To assess the efficacy of coenzyme Q10 (CoQ10) as an adjunct to nonsurgical periodontal therapy and its effect on superoxide dismutase (SOD) in gingival crevicular fluid (GCF) in patients with chronic periodontitis (CP). Materials and Methods?A total of 16 patients aged between 30 and 50 years having mild to moderate CP of both sexes having pocket depth of 5 to 7 mm in four nonadjacent interproximal sites were selected. The sites were randomized and divided into treatment and control groups. CoQ10 and a placebo gel were administered in the treatment and control sites, respectively, at baseline after scaling and root planing (SRP). GCF was collected using microcapillary method at baseline and 3 months and was assessed for SOD using enzyme-linked immunosorbent assay reader at 450 nm wavelength. Probing pocket depth, gingival index, and plaque index were assessed at baseline, 1 month, and 3 months, respectively. Statistical analysis?For each assessment point, data were statistically analyzed using Student’s t-test and paired t-test. Level of significance was set at p 0.05. Results?On intergroup comparison, there was no statistically significant difference between the clinical parameters of both the groups at all the time intervals (p 0.05), but there was a significant increase in the level of SOD in the test group (p 0.05) compared with the control group at 3 months. Conclusions?Adjunctive use of CoQ10 with SRP can boost the antioxidant concentration, but it is not superior to SRP in the treatment of CP.
机译：目的是评估辅酶Q10（COQ10）作为非牙科牙周治疗（CP）术患者牙龈沟槽（GCF）中超氧化物歧化酶（SOD）的辅助效果的疗效。材料和方法？选择了16岁至50岁的患者，在四个非加入焦点位点中具有5至7毫米的两性中的温和至中度Cp。该部位随机化并分为治疗和对照组。在缩放和根刨（SRP）后，分别在基线施用CoQ10和安慰剂凝胶。使用基线和3个月在基线中使用微毛细管法收集GCF，并在450nm波长下使用酶联免疫吸附测定读取器进行SOD。在基线，1个月和3个月内评估探测口袋深度，牙龈指数和斑块指数。统计分析？对于每个评估点，使用学生的T检验和配对T检验进行统计分析数据。显着性级别设定为P <0.05。结果？在互组比较中，所有时间间隔的组临床参数之间没有统计学上有显着差异（P> 0.05），但试验组中的SOD水平显着增加（P> 0.05 ）与3个月的对照组进行比较。结论？辅助使用SRP的CoQ10可以提高抗氧化剂浓度，但在CP的治疗中不优于SRP。

著录项

相似文献

  • 外文文献
  • 中文文献
  • 专利
获取原文

客服邮箱：kefu@zhangqiaokeyan.com

京公网安备：11010802029741号 ICP备案号：京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有

  • 客服微信

  • 服务号