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Genomic diversity and selection sweeps identified in Indian swamp buffaloes reveals its uniqueness with riverine buffaloes

机译:印度沼泽水牛中鉴定的基因组多样性和选择扫描揭示了其与河流水牛的独特性

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The present investigation was focused to study genomic diversity of Indian swamp buffalo populations through reduced representation approach (ddRAD). The heterozygosity (FST) among the swamp buffaloes was 0.11 between Assam and Manipuri; 0.20 between swamp (Manipuri) and riverine buffaloes; 0.30 between swamp (Manipuri) and cattle. The average observed and expected heterozygosity in swamp buffalo populations was 0.254 and 0.221 respectively. The Inbreeding coefficient (FIS) value was 0.02 among the swamp buffaloes. PCA and structure analysis revealed Manipuri swamp buffalo was genetically distinct and closely related to Nagaland swamp buffalo and least to Assam swamp buffalo. Identification of selective sweeps revealed 1087 regions to have undergone selection related to immune response, adaptation and nervous system. A total of 3451 SSRs were identified in the genome of swamp buffaloes. The study evidenced the genomic diversity in the swamp buffalo populations and its uniqueness in comparison with riverine buffalo and cattle.
机译:目前的调查集中于通过减少的代表方法(DDRAD)研究印度沼泽布法罗群体的基因组多样性。沼泽水牛中的杂合子(FST)在Assam和Manipuri之间为0.11;沼泽(Manipuri)和Riverine Buffaloes之间的0.20;沼泽(Manipuri)和牛之间的0.30。沼泽性水牛群中的平均观察和预期的杂合性分别为0.254和0.221。沼泽地繁变的系数(FIS)值是沼泽性水牛中的0.02。 PCA和结构分析揭示了Manipuri Swamp Buffalo在基因上截然不同,与Nagaland Swamp Buffalo密切相关,最少地与Assam Swamp Buffalo密切相关。选择性扫描的鉴定揭示了1087个地区,与免疫反应,适应和神经系统有关的选择。在沼泽水牛的基因组中,共鉴定了3451个SSR。该研究证明了沼泽布法罗群体的基因组多样性及其独特性与河流水牛和牛相比。

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