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首页> 外文期刊>Food Science & Nutrition >Effects of synbiotics containing Bifidobacterium animalis subsp. lactis GCL2505 and inulin on intestinal bifidobacteria: A randomized, placebo‐controlled, crossover study
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Effects of synbiotics containing Bifidobacterium animalis subsp. lactis GCL2505 and inulin on intestinal bifidobacteria: A randomized, placebo‐controlled, crossover study

机译：含有双歧杆菌胚瓣的同步的影响。乳酸Gcl2505和菊粉对肠道双歧杆菌：随机，安慰剂控制，交叉研究

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A number of studies have shown the bifidogenic effects of either probiotic bifidobacteria or inulin, and this bifidogenic shift in the composition of the colonic microbiota is likely the basis for their positive impact on human health. This study aimed to evaluate the effects of synbiotics containing the probiotic bacterium Bifidobacterium animalis subsp. lactis ( B.?lactis ) GCL2505 and inulin on the levels of intestinal bifidobacteria compared with B.?lactis GCL2505 alone. A randomized, double‐blind, placebo‐controlled, crossover trial was carried out involving 60 healthy subjects with a tendency for constipation using fermented milk containing B.?lactis GCL2505 and inulin (synbiotic), only B.?lactis GCL2505 (probiotic), and placebo. Fecal samples were collected at the end of each 2‐week intervention period, and the bifidobacterial count was analyzed by quantitative real‐time PCR. The numbers of total bifidobacteria and B.?lactis in feces were significantly increased during the probiotic and synbiotic intake periods compared with the placebo intake period. Furthermore, the numbers of total bifidobacteria and endogenous bifidobacteria were significantly higher in the synbiotic intake period compared with the probiotic intake period, while there was no difference in the number of B.?lactis . These results suggested that the synbiotics containing B.?lactis GCL2505 and inulin had a greater effect on the number of bifidobacteria than a drink containing probiotics alone and could be useful for the improvement of the intestinal environment.
机译：许多研究表明益生菌双歧杆菌或菊粉的双歧糖作用，结肠微生物群组合物中的这种双歧膜变化可能是它们对人体健康产生积极影响的基础。本研究旨在评估含有益生菌双歧杆菌胚子的同步的影响。乳酸（B.?曲面）GCL2505和inulin与单独的B.?粘接GCL2505相比的肠道双歧杆菌水平。随机，双盲，安慰剂控制的交叉试验，涉及使用含有B.?粘土GCL2505和菊粉（Synbiotic）的发酵乳的便秘倾向，仅为B.?曲率为GCl2505（益生菌），和安慰剂。在每个2周干预期结束时收集粪便样品，通过定量实时PCR分析双歧杆菌计数。与安慰剂摄入期相比，在益生菌和同步进气期间，粪便中总双歧杆菌和B.?曲率的数量显着增加。此外，与益生菌进气期相比，Synbiotic Intrake时期的总双歧杆菌和内源性双歧杆菌的数量显着高，而B.?乳糜的数量没有差异。这些结果表明，含有B.?曲面的Synbiotics G .?曲曲面GCL2505和菊粉对单独的双歧杆菌的数量具有比单独含益生菌的饮料更大的效果，并且可用于改善肠环境。

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