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The efficacy and safety of Xuebijing injection as an adjunctive treatment for acute pancreatitis: Protocol for a systematic review and meta-analysis of randomized controlled trials

机译：Xuebijing注入作为急性胰腺炎的辅助治疗的疗效和安全性：随机对照试验的系统评论和荟萃分析的议定书

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摘要

Background: Acute pancreatitis (AP) is one of the common diseases with increasing incidence in clinical surgery and other gastrointestinal-digestive departments. Despite the rapid development of modern medicine, the overall mortality rate of AP is still high. Xuebijing (XBJ) injection (a traditional Chinese patent medicine) is a potentially effective drug for AP. This study is designed to assess the efficacy and safety of XBJ injection for AP. Methods: We will extract data and assess methodological quality of included studies from 7 electronic databases from their inception to December 31, 2019. The primary outcomes include the mortality, surgical intervention, systemic inflammatory response syndrome (SIRS), local complications, systemic infections, gastrointestinal symptoms, and normal blood amylase recovery time. The statistical analysis will be performed using RevMan 5.3 software. Results: This study will provide high-quality evidence for the efficacy of XBJ injection as an adjuvant therapy for AP. Conclusion: The study will provide the key evidence for clinical doctors and the development of clinical guidelines.
机译：背景：急性胰腺炎（AP）是临床手术和其他胃肠道消化系统患者发病率越来越多的常见疾病之一。尽管现代医学的发展迅速，但AP的总体死亡率仍然很高。 Xuebijing（XBJ）注射（传统的中国专利医学）是AP的潜在有效的药物。本研究旨在评估AP XBJ注射的疗效和安全性。方法：我们将提取数据和评估从7个电子数据库的研究结果从2019年12月31日开始的研究。主要结果包括死亡率，手术干预，全身性炎症反应综合征（SIRS），局部并发症，全身感染，胃肠道症状，常规血液淀粉酶恢复时间。统计分析将使用Revman 5.3软件进行。结果：本研究将为XBJ注射作为AP的佐剂治疗提供高质量证据。结论：该研究将为临床医生提供关键证据和临床指南的发展。

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