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首页> 外文期刊>The Journal of toxicological sciences >Microarray analysis of differentially expressed gene responses to bisphenol A in Arabidopsis
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Microarray analysis of differentially expressed gene responses to bisphenol A in Arabidopsis

机译：拟南芥对双酚A差异表达基因反应的微阵列分析

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Environmental levels of bisphenol A (BPA) are a global concern because the compound can cause damage to reproductive organs, the thyroid gland, and brain tissues at developmental stages. Plants are important in removing BPA from the atmosphere, soil, and water. However, knowledge on the mechanism by which plants respond to this compound is limited. To determine the response mechanism of plants to BPA, we used a microarray system to analyze the gene expression patterns of Arabidopsis thaliana after irrigation with 3.0 mM BPA. We identified 651 genes that were differentially expressed upregulated and 470 genes that were downregulated by BPA. These genes may specifically contribute to BPA uptake, transformation, conjugation, and compartmentation in plants. The potential function of upregulated genes in plant defense against BPA was also determined.
机译：双酚A（BPA）的环境水平是全球担忧，因为该化合物可损害生殖器官，甲状腺和发育阶段的脑组织。植物在从大气，土壤和水中移除BPA很重要。然而，有关植物对该化合物的响应的机制的知识是有限的。为了确定植物对BPA的响应机制，我们使用了微阵列系统以分析3.0mM BPA灌溉后拟南芥的基因表达模式。我们鉴定了651个基因，其差异表达上调和470个基因由BPA下调。这些基因可以特别有助于BPA吸收，转化，缀合和植物中的隔音。还确定了对BPA植物防御植物防御的上调基因的潜在功能。

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