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Evaluation of Oxidative Stress, Antioxidant Power, and Antioxidant Potential of Breastmilk of Breast-Feeding Mothers

机译:乳化母乳喂养母乳母乳母乳母乳的氧化应激,抗氧化能力和抗氧化剂潜力的评价

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Purpose: The purpose of this study was to evaluate oxidative stress, antioxidant power, and antioxidant potential of breastmilk of breast-feeding mothers from the early postpartum period to the first 3 months postpartum, and to examine the dynamics and the relationships among them. Method: For 47 pu-erperant women who gave vaginal birth without any pregnancy complications, the oxidative stress levels (d-ROMs levels) and antioxidant power (BAP levels) in the maternal plasma as well as antioxidant potential of breastmilk (BAP levels in breastmilk) were measured 3 times, i.e., in the early puerperium (4 or 5 days after giving birth), one month after giving birth, and 3 months after giving birth. Results: The d-ROMs levels in the maternal plasma were significantly high in the early puerperium (p < 0.001), and decreased gradually in the post-partum period (p < 0.001). On the other hand, BAP levels were significantly low in the early puerperium (p < 0.001), and increased to the almost normal level during one month after giving birth. BAP levels in breastmilk were significantly high in the early puerperium compared with the other periods (p < 0.001), and decreased gradually until 3 months after giving birth (p < 0.001). BAP levels in breastmilk in the early puerperium were higher compared with the maternal BAP levels, and there was a positive correlation between BAP levels in breast-milk and those in the maternal plasma (p < 0.05). Discussion: Regarding the oxidative stress and the antioxidant defense system of breast-feeding mothers, the d-ROMs level was highest and the BAP level was lowest in the early puerperium. The BAP level then showed a clear tendency to recover in the first 3 months after giving birth. Conclusion: When the maternal antioxidant potential remains at a low level after giving birth, careful consideration should be given to the mother’s health and wellbeing because there is a possibility that it might affect the antioxidant potential of breastmilk.
机译:目的:本研究的目的是评估母乳喂养母亲母乳母乳的氧化应激,抗氧化能力和抗氧化剂潜力从产后早期到前3个月,并检查动态和它们之间的关系。方法:对于母体血浆的氧化应激水平(D-ROM水平)和抗氧化潜力(D-ROM水平)和抗氧化剂潜力(母乳的抗氧化剂潜力(母乳中的抗氧化剂潜力)给阴道出生)被测量3次,即在呕吐早期(出生后4或5天),分娩后一个月,分娩后3个月。结果:早期产褥期(P <0.001)中母体血浆中的D-ROM水平显着高(P <0.001),逐渐减少( P <0.001)。另一方面,早期产褥期( P <0.001),BAP水平显着低,并在分娩后一个月内增加到几个正常水平。早期产褥期母乳中的BAP水平与其他时期( P <0.001)相比显着高,并逐渐降低至出生后3个月( P <0.001) 。与母体BAP水平相比,乳头钙早期产褥期的BAP水平较高,母乳中的BAP水平与母体等离子体中的阳性相关性( P <0.05)。讨论:关于哺乳母亲的氧化应激和抗氧化剂防御系统,D-ROM水平最高,并且在产褥期早期的BAP水平最低。然后,BAP水平显示出在分娩后的前3个月内恢复的明显倾向。结论:当母体抗氧化潜力仍然处于分娩后仍处于低水平,应仔细考虑母亲的健康和福祉,因为可能会影响母乳的抗氧化潜力。

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