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首页> 外文期刊>Journal of Oral Microbiology >Salivary microbiota in individuals with different levels of caries experience
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Salivary microbiota in individuals with different levels of caries experience

机译：唾液微生物在具有不同水平的龋齿经验

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This study compared salivary bacterial profiles in two groups having a 10-fold difference in levels of caries experience, as it was hypothesized that the composition of the salivary microbiota might associate with the levels of caries experience.Bacterial profiles in stimulated saliva samples from 85 individuals with low levels of caries experience (healthy group) and 79 individuals with high levels of caries experience (caries group) were analyzed by means of the Human Oral Microbiome Identification Next Generation Sequencing (HOMINGS) technique. Subsequently, saliva samples from caries-free individuals in the healthy group (n?=?57) and the caries group (n?=?31) were compared.A significantly higher α-diversity (p??0.0001) and a twofold higher relative abundance of Neisseria, Haemophilus, and Fusobacterium were recorded in saliva samples from the healthy group compared with the caries group. Differences observed were more pronounced when limiting the analyses to caries-free individuals in each gr...
机译：该研究将唾液菌细菌谱系于两组中具有10倍差异的龋齿体验差异，因为它的假设是唾液微生物群的组成可能与龋齿体验的水平相关联。刺激的唾液样本中的刺激物曲线来自85个通过人口服微生物微生物综合鉴定下一代测序（归属）技术，分析了低水平的龋齿经验（健康组）和79个具有高水平龋齿经验（龋齿组）的人。随后，比较来自健康组的无龋齿的唾液样品（n？=Δ57）和龋齿组（n？= 31）。a显着更高的α-多样性（p？<？0.0001）和双重与龋齿组相比，在健康组的唾液样本中记录了唾液遗传症，嗜血杆菌和Fusobacterium的相对丰度。当将分析限制在每个GR中的无龋齿的分析时，观察到的差异更加明显......

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