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首页> 外文期刊>Journal of Research in Dental Sciences >Comparison of Antibacterial Effect of Nanosilver and Chlorhexidine Mouthwash on Streptococcus Sanguis (in vitro)
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Comparison of Antibacterial Effect of Nanosilver and Chlorhexidine Mouthwash on Streptococcus Sanguis (in vitro)

机译：纳米玻璃和氯己定漱口水对链球菌的抗菌作用的比较（体外）

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Background and Aim: Streptococcus sanguis is known one of the initiating agents of microbial plaque formation.In addition to the physical control of the microbial plaque, the use of mouthwashes as a chemical method to kill microorganisms is effective.Although chlorhexidine is the gold standard for the elimination of oral microorganisms, the unpleasant side effects of its long-term use warrant a more appropriate alternative.The purpose of this study was to compare the antibacterial effect of nanosilver and chlorhexidine mouthwash on Streptococcus sanguis in pediatric department, faculty of Dentistry, Tehran Medical Sciences, Islamic Azad University in 2018-19.Materials and methods: This experimental study was performed on Streptococcus sanguis (in vitro).Experiments were performed on two groups of case (nanosilver mouthwash) and control (chlorhexidine mouthwash) in three parts Initially, antimicrobial potency was measured by Disk diffusion method assay by measuring inhibitory zone diameter.Then, micro and macrodialysis methods were used to measure MIC (minimum inhibitory concentration) and finally to measure MBC (minimum bactericidal concentration) used the Blood agar dilution method.Results: Statistical analysis showed that the nanosilver mouthwash has no inhibitory zone.Also its MIC and MBC were higher than chlorhexine and this difference was statistically significant (P <0.001) Conclusion: According to the results of the in vitro study nanosilver mouthwashhas minor bacteriostatic and bactericidal effect compared to chlorhexidine.
机译：背景和目的：链球菌是已知的微生物斑块形成的引发剂之一。除了微生物斑块的物理控制外，漱口水作为杀灭微生物的化学方法是有效的。虽然氯己定是金标准消除口服微生物，其长期使用的令人不愉快的副作用是更合适的替代方案。本研究的目的是比较纳米ilver和氯己定漱口水对牙科牙科牙科教师患者的链球菌患者的抗菌作用2018 - 198年至19日伊斯兰·阿扎德大学的医学科学及方法：对血栓球菌（体外）进行的该实验研究进行了两组案例（纳米液漱口水溶液）和最初的控制（氯己定漱口水）。 ，通过测量抑制区径向磁盘扩散法测定抗微生物效力用于测量MIC（最小抑制浓度），最终测量MBC（最小杀菌浓度）使用血液琼脂稀释方法。结果：统计分析表明，纳米液漱口水没有抑制区.ALSO其MIC和MBC高于氯化物，这种差异有统计学意义（P <0.001）结论：根据体外研究的结果，与氯己定相比，纳米ilm嘴淋巴瘤的轻微噬菌体和杀菌效果。

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