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首页> 外文期刊>Journal of Young Pharmacists >Implementation of a Drug Allergy Testing Service in the Dermatology Outpatient Clinic of a Public University Hospital
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Implementation of a Drug Allergy Testing Service in the Dermatology Outpatient Clinic of a Public University Hospital

机译：公立大学医院皮肤病学门诊诊所的实施

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Background: Investigation based solely on clinical history background is not sufficient to prove drug allergy and may lead to search for more expensive and potentially less effective alternative drugs. There are too few health centers that perform such tests in Brazil. Objectives: The aim of the present work was to structure and to systematize a service for in vivo drug skin testing in a public university hospital. Methods: The project was structured as follows: a) Divulgation about the service among health professionals and also among patients; b) Active search for suspicious cases; d) Referral to the allergist consultation; c) Performance of skin prick, intradermal and/or epicutaneous tests when requested. Results: Disclosure about the service was done through informal talk, workshop, flyers, advertisement. Active search for suspicious cases was done at the Dermatology Outpatient Clinics, Walter Cantídio Hospital School, Brazil. Ninety patients were evaluated by the allergist, and from these, 68 were submitted to drug skin tests. Thirty-five patients out of 68 presented clinical manifestations up to 2 h after drug intake and 33, more than 2h after drug intake. The drugs most implicated were NSAIDS and β-lactam drugs. Seventy-seven tests carried out. For immediate reading, 41 puncture tests and 12 intradermal tests were performed. For delayed reading, 24 epicutaneous tests were done. Two patients presented positive prick test to dipyrone. Conclusion: For implementing an adequate and effective service for drug skin testing, technical and practical training of health professionals about drug safety is necessary, besides interdisciplinary collaboration and an adequate support by the hospital managers.
机译：背景：仅基于临床历史背景的调查不足以证明药物过敏，可能导致寻求更昂贵和潜在的较低的替代药物。在巴西在巴西进行了这种测试的健康中心太少。目的：目前工作的目的是结构，并在公立大学医院进行体内药物测试的服务。方法：该项目的结构如下：a）卫生专业人士和患者之间的服务的泄露; b）积极搜索可疑病例; d）转诊到过敏师咨询; c）在要求时表现皮肤刺，皮内和/或面​​膜测试。结果：关于该服务的披露是通过非正式谈话，研讨会，传单，广告完成的。积极搜索可疑病例的皮肤科门诊诊所，巴西沃尔特坎塔迪奥医院的皮肤科门诊诊所完成。通过过敏症评估了九十名患者，从而提出68例药物皮肤测试。三十五名患者在68例中呈现临床表现，可在药物摄入后高达2小时，药物摄入后23次，超过2小时。最牵连的药物是NSAIDS和β-内酰胺药物。进行了七十七次测试。对于立即读数，进行了41个穿刺试验和12个皮内测试。对于延迟读数，完成了24次积膜。两名患者向偶联金呈现出阳性刺试验。结论：除了跨学科合作以及医院管理人员的跨学科和适当的支持，还需要对药物皮肤测试的适当有效的药物皮肤测试服务，卫生专业人员的技术和实践培训。

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