• 主题
高级搜索  >
历史搜索 清空历史
首页> 外文期刊>Journal of Transfusion >Quality of Red Blood Cells Isolated from Umbilical Cord Blood Stored at Room Temperature
【24h】

Quality of Red Blood Cells Isolated from Umbilical Cord Blood Stored at Room Temperature

机译：从脐带血液中分离的红细胞质量储存在室温下

获取原文
           
页面导航
  • 摘要
  • 著录项
  • 相似文献
  • 相关主题

摘要

Red blood cells (RBCs) from cord blood contain fetal hemoglobin that is predominant in newborns and, therefore, may be more appropriate for neonatal transfusions than currently transfused adult RBCs. Post-collection, cord blood can be stored at room temperature for several days before it is processed for stem cells isolation, with little known about how these conditions affect currently discarded RBCs. The present study examined the effect of the duration cord blood spent at room temperature and other cord blood characteristics on cord RBC quality. RBCs were tested immediately after their isolation from cord blood using a broad panel of quality assays. No significant decrease in cord RBC quality was observed during the first 65 hours of storage at room temperature. The ratio of cord blood to anticoagulant was associated with RBC quality and needs to be optimized in future. This knowledge will assist in future development of cord RBC transfusion product.
机译：来自脐带血的红细胞（RBC）含有胎儿血红蛋白，其在新生儿中主要是占主导的，因此，比目前转染的成年RBC可能更适合新生儿输血。收集后，脐带血可以在室温下储存几天，然后处理干细胞分离，仔细了解这些条件如何影响目前丢弃的RBC。本研究检测了在室温下花费的持续时间脐带血和其他脐带血特性的效果。使用宽的质量测定分离在从脐带血中分离后立即进行RBC。在室温下储存的前65小时内未观察到帘线质量的显着降低。脐带血与抗凝血剂的比例与RBC质量有关，需要将来优化。这种知识将有助于未来的脐带RBC输血产品的发展。

著录项

相似文献

  • 外文文献
  • 中文文献
  • 专利
获取原文

客服邮箱：kefu@zhangqiaokeyan.com

京公网安备：11010802029741号 ICP备案号：京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有

  • 客服微信

  • 服务号