...
  • 主题
高级搜索  >
历史搜索 清空历史
首页> 外文期刊>Journal of Thoracic Disease >Investigation of a family cluster outbreak of COVID-19 indicates the necessity of CT screening for asymptomatic family members in close contact with confirmed patients
【24h】

Investigation of a family cluster outbreak of COVID-19 indicates the necessity of CT screening for asymptomatic family members in close contact with confirmed patients

机译：对Covid-19的家庭聚类爆发的调查表明，无症状家庭成员与确诊患者密切接触的CT筛选的必要性

获取原文
           
页面导航
  • 摘要
  • 著录项
  • 相似文献
  • 相关主题

摘要

Background: To investigate whether asymptomatic close-contact family members of patients diagnosed with coronavirus disease (COVID-19) should immediately undergo CT screening in addition to the viral nucleic acid test. Methods: We retrospectively analyzed the data of a family cluster of 8 individuals, of whom 1 family member (Patient 3) had an epidemiologic history of having visited Guangzhou from Hubei Province on January 20, 2020. Her father (Patient 1) developed a fever and respiratory system symptoms and was confirmed COVID-19-positive on February 4–5, 2020 at Zengcheng People’s Hospital, Guangzhou, China. Seven close-contact family members of the patients were then screened for COVID-19 on February 5–6 at the hospital. The CT imaging manifestation and laboratory tests of this family cluster were investigated and reported. Results: Five (62.5%) of the 8 family members were confirmed COVID-19-positive. Except for Patient 1, who had fever, cough, fatigue, and dizziness, the remaining four (4/5, 80%) COVID-19-positive family members (Patients 2–5) had no clinical symptoms. Among the 5 patients, 2 had leukopenia (2/5, 40%), 1 had low absolute neutrophil counts (1/5, 20%), and 2 had increased high-sensitivity C-reactive protein (2/5, 40%). Ground-glass opacity (GGO) was found on chest CT imaging in all 5 patients (5/5, 100%), with interlobular septal thickening. Thickened blood vessel shadows were seen in 3 patients (3/5, 60%). The 3 COVID-19-negative family members (Family Members 1–3) did not have CT abnormalities, and they showed negative reverse transcription-polymerase chain reaction (RT-PCR) results twice. Conclusions: CT screening is necessary in close-contact family members of a confirmed COVID-19 pneumonia case, regardless of the presence of clinical symptoms.
机译：背景：为了探讨是否患有冠状病毒疾病（Covid-19）的患者的无症状紧密联系家庭成员是否应立即进行CT筛选，除了病毒核酸试验。方法：我们回顾性地分析了8个个人的家族集群的数据，其中1名家庭成员（患者3）在2020年1月20日从湖北省访问广州的流行病学史。她的父亲（患者1）发烧了发烧和呼吸系统症状，并于2020年2月4日在中国广州曾城人民医院2月4日至5日确认了Covid-19正。然后在医院的2月5日至6日筛选患者的七个近距离家庭成员。研究并报告了该族聚类的CT成像表现和实验室测试。结果：8个家庭成员的五（62.5％）确认了Covid-19阳性。除了患者1，患者发烧，咳嗽，疲劳和头晕，其余四（4/5,80％）Covid-19阳性家庭成员（2-5患者）没有临床症状。在5名患者中，2例白细胞（2/5,40％），1个具有低的绝对中性粒细胞计数（1/5,20％），2例高敏感性C-反应蛋白（2/5,40％） ）。在所有5名患者（5/5,100％）的胸部CT成像中发现底玻璃不透明度（GGO），具有间隔子间隔增厚。 3名患者（3/5,60％）中看到增厚的血管阴影。 3 Covid-19阴性家庭成员（家庭成员1-3）没有CT异常，它们显示出负逆转录 - 聚合酶链反应（RT-PCR）结果两次。结论：无论存在临床症状，CT筛选是在确认的Covid-19肺炎案例的紧密系列成员中所必需的。

著录项

相似文献

  • 外文文献
  • 中文文献
  • 专利
获取原文

客服邮箱：kefu@zhangqiaokeyan.com

京公网安备：11010802029741号 ICP备案号：京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有

  • 客服微信

  • 服务号