• 主题
高级搜索  >
历史搜索 清空历史
首页> 外文期刊>RSC Advances >Synthesis of 2,4,5-trisubstituted imidazoles, quinoxalines and 1,5-benzodiazepines over an eco-friendly and highly efficient ZrO2–Al2O3 catalyst
【24h】

Synthesis of 2,4,5-trisubstituted imidazoles, quinoxalines and 1,5-benzodiazepines over an eco-friendly and highly efficient ZrO2–Al2O3 catalyst

机译：合成2,4,5-三取代的咪唑，喹喔啉和1,5-苯并二氮杂锌，通过生态友好且高效Zro2-Al2O3催化剂

获取原文
           
页面导航
  • 摘要
  • 著录项
  • 相似文献
  • 相关主题

摘要

ZrO _(2) –Al _(2) O _(3) containing 80 mol% of ZrO _(2) was prepared by solution combustion, impregnation and precipitation methods. All the prepared catalytic materials were characterized by PXRD, NH _(3) -TPD, N _(2) adsorption isotherms, FTIR, TEM, SEM, EDAX and ICP-OES techniques. These catalytic materials were used in a rapid, simple, versatile and efficient synthesis of 2,4,5-trisubstituted imidazoles under solvent-free conditions at moderate temperature in shorter reaction time (20 min). This is achieved by three-component cyclo-condensation of benzil, aldehydes and ammonium acetate in excellent yields. The derivatives of quinoxalines and 1,5-benzodiazepines were synthesized effectively by cyclo-condensation of 1,2-diamine with α-diketones and carbonyl compound with O -phenylenediamines respectively over ZrO _(2) –Al _(2) O _(3) at moderate temperature (80 °C) for the reaction time of 20–40 min in presence of ethanol as a solvent. The present method is experimentally simple, non-toxic and involves inexpensive reagents, clean reaction pathways and an eco-friendly catalyst. The catalytic materials used can be easily separated from the reaction mixture and reused for several reaction cycles without much loss of catalytic activity.
机译：通过溶液燃烧，浸渍和沉淀方法制备含有80摩尔％ZrO _（2）的ZrO _（2）-Al _（3）。所有制备的催化材料的特征在于PXRD，NH _（3）-TPD，N _（2）吸附等温，FTIR，TEM，SEM，edax和ICP-OES技术。这些催化材料在溶剂条件下在溶剂条件下在溶剂的条件下进行快速，简单，通畅，有效合成2,4,5-三取代的咪唑，以更短的反应时间（20分钟）。这是通过苯齐尔，醛和乙酸铵的三分组分环缩，优异的产率来实现。喹喔啉和1,5-苯二氮氧基己胺的衍生物通过分别在Zro _（2）-al _（2）O _（2）O _（2）O _（ 3）在乙醇作为溶剂的情况下，在中等温度（80℃）的反应时间为20-40分钟。本方法是实验简单，无毒的，涉及廉价的试剂，清洁反应途径和环保催化剂。所用催化材料可以容易地与反应混合物分离，并重复使用几种反应循环，而不会损失催化活性。

著录项

相似文献

  • 外文文献
  • 中文文献
  • 专利
获取原文

客服邮箱：kefu@zhangqiaokeyan.com

京公网安备：11010802029741号 ICP备案号：京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有

  • 客服微信

  • 服务号