A novel C–C radical–radical coupling reaction promoted by visible light: facile synthesis of 6-substituted N-methyl 5,6-dihydrobenzophenanthridine alkaloids

Zhaoying Liu; Yajun Huang; Hongqi Xie; Wei Liu; Jianguo Zeng; Pi Cheng

首页> 外文期刊>RSC Advances >A novel C–C radical–radical coupling reaction promoted by visible light: facile synthesis of 6-substituted N-methyl 5,6-dihydrobenzophenanthridine alkaloids

【24h】

A novel C–C radical–radical coupling reaction promoted by visible light: facile synthesis of 6-substituted N-methyl 5,6-dihydrobenzophenanthridine alkaloids

机译：通过可见光促进的新型C-C自由基偶联反应：容易合成6-取代的N-甲基5,6-二羟基苯蒽蒽生物碱

获取原文

掌桥外文数据库（机构版） >>

开具论文收录证明 >>

文献代查 >>

页面导航

摘要
著录项
相似文献
相关主题

摘要

A novel photoredox-mediated direct intermolecular C–H functionalization of N -methyl 5,6-dihydrobenzophenanthridine is developed utilizing the visible light-induced reductive quenching pathway of photocatalyst Ir(ppy) _(3) . In the proposed coupling mechanism, an α-amino C-radical is generated at the 6-position of N -methyl 5,6-dihydrobenzophenanthridine which is capable of coupling with α-EWG (electron withdrawing group) substituted C-radicals. The utility of this methodology has been demonstrated via rapid access to the analogue of natural 6-substituted N -methyl 5,6-dihydrobenzophenanthridine alkaloids.

机译：使用可见光诱导的光催化剂IR（PPY）_（3）的可见光诱导的还原猝灭途径开发了一种新型的光致毒介导的N-二氢苯蒽蒽醌的直肠分子间C-H官能化。在所提出的偶联机构中，在α-氨基C-基团的α-氨基C-基团处产生，其能够与α-EWG（电子取出基团）取代的C-基团偶联。通过快速进入自然6取代的N-二甲基蒽蒽生物碱的类似物质的快速进入来证明该方法的效用。

著录项

来源
《RSC Advances》 |2016年第56期|共6页
作者
Zhaoying Liu; Yajun Huang; Hongqi Xie; Wei Liu; Jianguo Zeng; Pi Cheng;
展开▼
作者单位

展开▼
收录信息
原文格式 PDF
正文语种
中图分类
关键词

相似文献

外文文献
中文文献
专利

1. A novel C-C radical-radical coupling reaction promoted by visible light: facile synthesis of 6-substituted N-methyl 5,6-dihydrobenzophenanthridine alkaloids [J] . Liu Zhaoying, Huang Yajun, Xie Hongqi, RSC Advances . 2016,第56期

机译：通过可见光促进的新型C-C自由基偶联反应：容易合成6-取代的N-甲基5,6-二羟基苯蒽蒽生物碱
2. Visible-Light-Promoted Photocatalytic B-C Coupling via a Boron-Centered Carboranyl Radical: Facile Synthesis of B(3)-Arylated o-Carboranes [J] . Zhao Da, Xie Zuowei Angewandte Chemie . 2016,第9期

机译：通过以硼为中心的碳硼烷基自由基的可见光促进光催化B-C耦合：方便的合成的B（3）-芳基化的o-碳硼烷
3. Visible-Light-Promoted Photocatalytic B-C Coupling via a Boron-Centered Carboranyl Radical: Facile Synthesis of B(3)-Arylated o-Carboranes [J] . Zhao Da, Xie Zuowei Angewandte Chemie . 2016,第9期

机译：通过以硼为中心的碳硼烷基自由基的可见光促进光催化B-C耦合：方便的合成的B（3）-芳基化的o-碳硼烷
4. THE USE OF ATOM TRANSFER RADICAL COUPLING REACTIONS FOR THE SYNTHESIS OF VARIOUS MACROMOLECULAR STRUCTURES [C] . Yasemin Yuksel Durmaz, Binnur Aydogan, Ioan Cianga, ACS symposium on controlled/living radical polymerization . 2009

机译：使用原子传递自由基偶联反应进行各种大分子结构的合成
5. Electroorganic synthesis: Inter- and intra-molecular anion radical cycloadditions, and electrogenerated base promoted coupling reactions. [D] . Felton, Greg Andrew Nicholas. 2005

机译：电有机合成：分子间和分子内阴离子自由基的环加成，以及电生成的碱促进的偶联反应。
6. Visible-light Promoted Atom Transfer Radical Addition−Elimination (ATRE) Reaction for the Synthesis of Fluoroalkylated Alkenes Using DMA as Electron-donor [O] . Wen-Wen Xu, Le Wang, Ting Mao, 2020

机译：可见光促进的原子转移自由基加成消除（ATRE）反应用于使用DMA作为电子给体的氟代烷基化烯烃的合成
7. Lewis Acid Activation of Fragment-Coupling Reactions of Tertiary Carbon Radicals Promoted by Visible-Light Irradiation of EDA Complexes [O] . -1

机译：EDA复合物可见光辐照促进叔碳基团的片段偶联反应的路易斯酸活化
8. Transition-Metal-Promoted Reactions of Boron Hydrides. 7. Platinum(II) Bromide Catalyzed Cage Growth and Dehydrocoupling Reactions of Diborane with Small Polyhedral Carboranes and Boranes: Synthesis of a New Arachno Carborane, 5,6-C2B6H12, and the Diborane-Coupled Compounds 2:1', 2'-(1,6-C2B4H5)(B2H5) and 2:1',2'-(B5H8)(B2H5). [R] . Corcoran, E. W., Sneddon, L. G. 1985

机译：过渡金属促进的氢化硼反应。 7.铂（II）溴化物催化的笼型生长和乙硼烷与小多面体碳硼烷和硼烷的脱氢偶联反应：合成新的arachno Carborane，5,6-C2B6H12和乙硼烷偶联化合物2：1'，2' - （ 1,6-C2B4H5）（B2H5）和2：1'，2' - （B5H8）（B2H5）。

A novel C–C radical–radical coupling reaction promoted by visible light: facile synthesis of 6-substituted N-methyl 5,6-dihydrobenzophenanthridine alkaloids

摘要

著录项

相似文献

相关主题

期刊订阅