Phosphine-catalyzed domino reactions of alkynyl ketones with sulfonylhydrazones: construction of diverse pyrazoloquinazoline derivatives

Qingqing Chen; Kaixuan Li; Tao Lu; Qingfa Zhou

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Phosphine-catalyzed domino reactions of alkynyl ketones with sulfonylhydrazones: construction of diverse pyrazoloquinazoline derivatives

机译：炔基酮与磺酰腙的膦催化的Domino反应：各种吡唑喹唑啉衍生物的构建

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An efficient method for the synthesis of C-1 position acyl substituted pyrazoloquinazoline derivatives via a PBu _(3) -promoted regioselective domino process of sulfonylhydrazones and alkynyl ketones was developed, which may be potentially useful for drug discovery.

机译：通过PBU _（3）-promoted的磺酰腙和炔基酮的HARKOMETED吡唑喹唑啉唑啉喹啉基础官衍生物的合成C-1位酰基取代的吡唑喹啉酮衍生物的有效方法进行了显影，这可能对药物发现可能有用。

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《RSC Advances》 |2016年第29期|共5页
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Qingqing Chen; Kaixuan Li; Tao Lu; Qingfa Zhou;
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1. Phosphine-catalyzed domino reactions of alkynyl ketones with sulfonylhydrazones: construction of diverse pyrazoloquinazoline derivatives [J] . Chen Qingqing, Li Kaixuan, Lu Tao, RSC Advances . 2016,第29期

机译：炔基酮与磺酰腙的膦催化的Domino反应：各种吡唑喹唑啉衍生物的构建
2. Diversified Construction of Chromeno[3,4-c]pyridin-5-one and Benzo[c]chromen-6-one Derivatives by Domino Reaction of 4-Alkynyl-2-oxo-2H-chromene-3-carbaldehydes [J] . Jian Xiao, Yuye Chen, Shuai Zhu Advanced synthesis & catalysis . 2014,第8期

机译：4-炔基-2-氧代-2H-色烯-3-甲醛的多米诺反应可多样化地构建Chromeno [3,4-c]吡啶-5-酮和苯并[c] chromen-6-酮衍生物
3. Phosphine-Catalyzed Domino Reaction of alpha,beta-Unsaturated Ketone and Allenoate: Stereoselective Synthesis of Polysubstituted Dihydro-2H-Pyran [J] . Li Jianxiong, Chen Yaoyao, Yuan Hongdong, Advanced synthesis & catalysis . 2018,第12期

机译：α，β-不饱和酮和甲酸酯的膦催化的Domino反应：多助化二氢-2H-吡喃的立体选择合成
4. Stereospecificity of the Gold(I)-cataIyzed reaction of 1-(1-alkynyl)-cyclopropyl Ketones with Nucleophiles. [C] . Stephan Labsch, Hans-Gunther Schmalz European Symposium on Organic Chemistry . 2009

机译：黄金（I）的立体特异性 - 1-（1-炔基） - 环丙基酮与亲核试剂的反应。
5. Multicomponent reactions of allenyl and alkynyl boron derivatives with amines and aldehydes and their use in the synthesis of novel multifunctional amines and heterocycles [D] . Liepouri, Fotini 2007

机译：烯丙基和炔基硼衍生物与胺和醛的多组分反应及其在合成新型多功能胺和杂环中的应用
6. Domino ring-opening–ring-closing enyne metathesis vs enyne metathesis of norbornene derivatives with alkynyl side chains. Construction of condensed polycarbocycles [O] . Ritabrata Datta, Subrata Ghosh 2018

机译：多米诺烯开环-闭环烯炔复分解与带有炔基侧链的降冰片烯衍生物的烯炔复分解。缩合聚碳环化合物的构建
7. Construction of 6-5-5-6-6 Pentacyclic Skeleton via a Phosphine-Catalyzed Domino Reaction and Mechanism Study [O] . -1

机译：通过膦催化的多米诺反应和机理研究构建五胞凝集骨骼骨架

Phosphine-catalyzed domino reactions of alkynyl ketones with sulfonylhydrazones: construction of diverse pyrazoloquinazoline derivatives

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