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首页> 外文期刊>Journal of Clinical and Diagnostic Research >Evaluation of Routine Coagulation Parameter in Suspected Acute Myocardial Infarction Patients Attending Emergency Department of Tertiary Care Hospital
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Evaluation of Routine Coagulation Parameter in Suspected Acute Myocardial Infarction Patients Attending Emergency Department of Tertiary Care Hospital

机译：涉嫌急性心肌梗死患者急性护理医院急性科病患者常规凝血参数评价

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摘要

Heart attack in medical terminology is generally called as Acute Myocardial Infarction (AMI).When blood flow is abruptly cut-off to the heart muscle, it damages the myocardial tissue.This could be the consequence of blocked coronary arteries.The plaque formed due to the deposition of cholesterol and other fatty material over a period of time is the leading cause of this blockage.Aim: To assess the level of Prothrombin Time (PT) and activated Partial Thromboplastin Time (aPTT) in cardiac and non-cardiac chest pain and their association to Body Mass Index (BMI).Materials and Methods: The present study was an observational case-control type of study which included 100 subjects of age group 30-65 years from March 2019 to April 2020.Out of them 50 were non-cardiac chest pain individuals which were control and 50 Cardiac chest pain arrived within 6-8 hours of chest pain who suspected to be Myocardial Infarction (MI) from Emergency Department, Dhiraj General Hospital, Gujarat, India.BMI was calculated by height and weight.PT and aPTT analysis was carried out using STAGO-S.A.S.coagulation analyser.Results: There were increased levels of PT and aPTT (statistically significant) in AMI cases compared to corresponding age and sex matched controls (p<0.0001).Pearson correlation analysis in AMI patients, a slightly positive correlation between BMI and aPTT was observed (r=0.19, p<0.001) and also between PT and aPTT (r=0.66, p<0.001).Conclusion: There was a slightly positive correlation found between BMI and aPTT which indicated that the weight and height of the patients do not affect the plasma PT and aPTT levels on anticoagulant therapy.
机译：医学术语中的心脏病发作一般被称为急性心肌梗死（AMI）。当血液流动突然切断到心脏肌肉时，它会损害心肌组织。这可能是阻塞冠状动脉的结果。由于在一段时间内沉积胆固醇和其他脂肪物质是这种堵塞的主要原因：评估凝血酶原时间（Pt）的水平和活性的部分血栓形成时间（Aptt）心脏和非心胸胸部疼痛他们与体重指数（BMI）的关联。材料和方法：本研究是一种观察病例对照类型的研究，其中包括从2019年3月至4月20日期间的30-65岁的100个年龄组科目。其中50个是非-Cardiac胸部疼痛个体被控制和50例心胸疼痛在胸痛6-8小时内到达，胸部疼痛是来自急诊部门，古吉拉特，印度古吉拉特邦的急诊肿症（MI）.BMI是C.通过高度和体重酰化和APTT分析进行使用STAGO-Sascoagulation分析。结果：与相应的年龄和性匹配对照组相比，AMI病例中的Pt和Aptt（统计学意义）水平增加（P <0.0001） 。在AMI患者中，观察到BMI和APTT之间的略微正相关（R = 0.19，P <0.001），也是在PT和APTT（r = 0.66，P <0.001）之间进行略微正相关。结论：略微阳性BMI和的aPTT之间的相关性发现，其表明，病人的体重和身高不影响等离子体PT和的aPTT水平上抗凝血疗法。

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