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首页> 外文期刊>Journal of Clinical and Diagnostic Research >Tear Film Changes in Type II Diabetes Mellitus with and without Diabetic Retinopathy
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Tear Film Changes in Type II Diabetes Mellitus with and without Diabetic Retinopathy

机译：II型糖尿病患者的撕裂膜变化，有糖尿病视网膜病变

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With the substantial progress in understanding of the ocular surface system in the past decade, Dry Eye Disease (DED) is the more commonly encountered condition in diabetes.Diabetes and DED have a common association.Aim: To estimate the prevalence of dry eye in diabetic patient and tear film changes with Diabetic Retinopathy (DR).Materials and Methods: It was an observational crosssectional study, in which 103 type II diabetic patients attending the Department of Ophthalmology in a Tertiary Care Hospital were enrolled, out of which 43 patients had DR and 60 patients had no DR.Dry eye evaluation was done using Ocular Surface Disease Indexing (OSDI) questionnaire and was confirmed objectively using Schirmer’s I and II test and Tear film Break Up Time (TBUT).Statistical Package for the Social Sciences (SPSS) version 20 was used for statistical analysis of this study data.All quantitative data were analysed by using parametric test whereas all qualitative data were analysed by using nonparametric test to find significance level and the p-value <0.05 was considered significant.Results: In present study, 68 among 103 diabetics patients had DED with the prevalence of 66% based on OSDI scoring.Out of the 43 patients with DR and 60 without DR, DED was encountered in 38 and 30 patients, respectively.DED status was not influenced by gender, age and duration of diabetes.An increase in DED was seen with higher HbA1c (Glycated Haemoglobin) values but was not significant.DED in DR group yielded a significant association with OSDI (p=0.002), Schirmer’s I and II (p=0.001) and TBUT (p=0.046).Conclusion: On the basis of present study, it can be stated that the prevalence of dry eye was more in DR patients in comparison to those without retinopathy.Therefore, all diabetic patients should be screened for dry eye, in order to diagnose and treat it at the earliest.
机译：随着在过去十年中对眼部系统的实质性进展，干眼症（DED）是糖尿病越常见的病情。Diabetes和DED有一个共同的协会。估计糖尿病患者干眼症的患病率患者和撕裂膜随患糖尿病视网膜病变（DR）。材料和方法：是一种观察性译，其中103型II型糖尿病患者参加了第三级护理医院的眼科部门部门，其中43名患者有博士60名患者没有Dr.dry眼睛评估是使用眼部疾病指数（OSDI）问卷进行的，并且客观地使用Schirmer的I和II测试和撕裂膜破碎时间（TBUT）。社会科学的统计包装（SPSS）版本20用于该研究数据的统计分析。通过使用参数测试分析了定量数据，而使用NonPar分析所有定性数据Ametric测试以寻找显着性水平和P值<0.05被认为是显着的。结果：在目前的研究中，103例糖尿病患者中的68名基于OSDI评分的患病率为66％，43名患者博士和60名患者没有DR，DED在38和30名患者中遇到了.Ded状态并不受到性别，年龄和糖尿病持续时间的影响。用较高的HBA1C（糖化血红蛋白）值观察到DED的增加，但并不重要。组与OSDI（p = 0.002），舒氏I和II（p = 0.001）和TBUT（P = 0.046）。结论：在本研究的基础上，可以说干眼症的患病率与没有视网膜病变的人相比，博士患者更多。因此，所有糖尿病患者都应该筛选干眼症，以最早诊断和治疗。

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