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首页> 外文期刊>Journal of International Medical Research >Systemic lupus erythematosus complicated with reversible posterior encephalopathy syndrome: a case report
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Systemic lupus erythematosus complicated with reversible posterior encephalopathy syndrome: a case report

机译：Systemic Lupus红斑和复杂的可逆后脑病综合征：案例报告

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A 28-year-old female patient was hospitalized primarily because of “intermittent fever for 28 days aggravated by systemic rashes, oral ulcer, and edema in both eyelids for 5 days.” During treatment, convulsions and loss of consciousness occurred. Magnetic resonance imaging (MRI) of the head revealed an abnormal signal with shadows in the bilateral frontal, parietal, temporal, and occipital lobes; cerebellar hemispheres; and basal nodes, with high signal intensity on T2 weighted imaging (T2WI), on fluid-attenuated inversion-recovery, and of the apparent diffusion coefficient and low signal intensity on T1WI and diffusion weighted imaging. Therefore, the patient was diagnosed with systemic lupus erythematosus (SLE) with reversible posterior encephalopathy syndrome (RPES). Intravenous high-dose methylprednisolone and cyclophosphamide were administered for blood pressure control, which effectively controlled the disease. Therefore, when patients with SLE and hypertension or renal insufficiency or those receiving high-dose methylprednisolone or immunosuppressants suddenly present with neurologic abnormalities, a diagnosis of RPES must be considered, and head MRI is the first choice for diagnosis of this disease. In terms of treatment, the blood pressure should be quickly controlled, and the primary disease should be aggressively treated.
机译：一名28岁的女病人主要因素为主要因素而入住，因为“28天的间歇性发烧28天，在眼睑下，口腔，口腔溃疡和水肿，5天。”在治疗过程中，发生了抽搐和意识丧失。头部的磁共振成像（MRI）揭示了双侧正面，垂体，时间和枕叶中的阴影的异常信号;小脑半球;和基础节点，在T2加权成像（T2WI）上具有高信号强度，对流体衰减的反转恢复以及表观扩散系数和T1WI和扩散加权成像的表观漫射系数和低信号强度。因此，患者被诊断患有可逆后脑病综合征（RPE）的全身狼疮红斑（SLE）。施用静脉注射高剂量甲基丙酮和环膦酰胺用于血压控制，有效控制疾病。因此，当患有SLE和高血压或肾功能不全或接受高剂量甲基丙酮或免疫抑制剂的患者突然存在神经系统异常时，必须考虑诊断RPE，头部MRI是诊断该疾病的首选。在治疗方面，应快速控制血压，并且应积极治疗原发性疾病。

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