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首页> 外文期刊>BMC Pregnancy and Childbirth >Pregnancy outcomes in women with infertility and coexisting endometriosis and adenomyosis after laparoscopic surgery: a long-term retrospective follow-up study
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Pregnancy outcomes in women with infertility and coexisting endometriosis and adenomyosis after laparoscopic surgery: a long-term retrospective follow-up study

机译：腹腔镜手术后患有不孕症和子宫内膜异位症和腺瘤患者的孕妇的妊娠结果：长期回顾性随访研究

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摘要

Adenomyosis (AM) and endometriosis (EM) often coexist. Laparoscopic surgery is one of the main methods for diagnosing and treating these conditions. This study aims to investigate the pregnancy outcomes of women with infertility with both AM and EM after laparoscopic surgery and to identify the relevant associated factors. This is a retrospective study involving women with infertility diagnosed with EM and AM. All patients had undergone laparoscopic surgery and were divided into two groups according to their pregnancy outcomes. Demographic data, operation records, and pregnancy outcomes were collected. A total of 226 female patients with infertility diagnosed with both AM and EM underwent laparoscopic surgery. Of these, a total of 176 patients completed follow-up. Ninety-seven patients had live births, including 81 full-term and 16 preterm deliveries. The clinical pregnancy and live birth rates were 67.4 and 55.11%, respectively. One hundred thirty-five patients received in vitro fertilization (IVF), with 70 (51.85%) of these patients having live births. Age, endometrioma size, and uterus size were significantly lower in those who had a successful delivery. There was no statistically significant difference in symptoms, except that those who achieved live birth had a lower rate of anaemia (13.40% vs. 25.32%, p?=?0.044). The group that did not proceed to have a live birth had a higher percentage of ovarian and peritoneal endometriosis (p??0.05), while the distribution of deep infiltrating endometriosis and adenomyosis types were similar. Mean uterus diameter (OR: 0.636, 95% CI: 0.434–0.932, p?=?0.020) and endometriosis fertility index (EFI) (OR: 1.299, 95% CI: 1.101–1.531, p?=?0.002) were significantly correlated with live birth in the multivariable analysis. Endometriosis and adenomyosis appear to have an adverse effect on pregnancy outcome. These might be related to the size of the uterus and EFI. Obstetricians and gynaecologists should be alert to this potential adverse effect and manage these patients accordingly.
机译：腺瘤（AM）和子宫内膜异位症（EM）经常共存。腹腔镜手术是诊断和治疗这些条件的主要方法之一。本研究旨在调查腹腔镜手术后AM和EM和EM患有不孕症的妊娠晚期，并确定相关的相关因素。这是一种涉及患有EM和AM诊断不孕症的妇女的回顾性研究。所有患者都经历了腹腔镜手术，并根据其妊娠结果分为两组。收集人口统计数据，操作记录和怀孕结果。共有226名女性患者诊断患有AM和EM接受腹腔镜手术的不孕症。其中，共有176名患者完成后续行动。九十七名患者患有活产，包括81个全冠和16个早产。临床妊娠和活产率分别为67.4和55.11％。一百三十五名患者接受体外施肥（IVF），其中70例（51.85％）这些患者患有活产。在成功交货的人中，年龄，子宫内膜瘤规模和子宫尺寸明显较低。症状没有统计学意义差异，除了那些达到活产出生的人贫血率较低（13.40％对25.32％，p？= 0.044）。没有继续存在的小组具有更高的卵巢和腹膜内膜异位症的百分比（P≤≤0.05），而深入渗透子宫内膜异位症和腺梗死类型的分布是相似的。平均子宫直径（或：0.636,95％CI：0.434-0.932，p？= 0.020）和子宫内膜异位症生育指数（或：1.299,95％CI：1.101-1.53​​1，P？= 0.002）显着在多变量分析中与活产出相关。子宫内膜异位症和腺小症似乎对妊娠结果产生了不利影响。这些可能与子宫和EFI的大小有关。产科医生和妇科医生应该警惕这种潜在的不利影响，并相应地管理这些患者。

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