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首页> 外文期刊>The Journal of Veterinary Medical Science >Effect of supplementation with the reduced form of coenzyme Q10 on semen quality and antioxidant status in dogs with poor semen quality: Three case studies
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Effect of supplementation with the reduced form of coenzyme Q10 on semen quality and antioxidant status in dogs with poor semen quality: Three case studies

机译:辅酶Q10减少对肝精液质量差的精液质量和抗氧化状态的影响:三种案例研究

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摘要

Oxidative stress owing to an imbalance between reactive oxygen species and antioxidants, such as coenzyme Q10 (CoQ10), is a major contributor to male infertility. We investigated the effects of the reduced form of CoQ10 (ubiquinol) supplementation on semen quality in dogs with poor semen quality. Three dogs received 100 mg of ubiquinol orally once daily for 12 weeks. Semen quality, serum testosterone, and seminal plasma superoxide dismutase (SOD) activity were examined at 2-week intervals from 2 weeks before ubiquinol supplementation to 4 weeks after the treatment. Ubiquinol improved sperm motility, reduced morphologically abnormal sperm, and increased seminal plasma SOD activity; however, it had no effect on testosterone level, semen volume, and sperm number. Ubiquinol supplementation could be used as a non-endocrine therapy for infertile dogs.
机译:由于反应性氧物质和抗氧化剂(例如辅酶Q10(COQ10)之间的不平衡,氧化应激是男性不孕症的主要因素。 我们调查了CQ10(Ubiquinol)补充剂的减少形式对精液质量差的狗精液质量的影响。 三只狗每天口服100毫升泛素蛋白,持续12周。 在治疗后4周前2周,在2周内以2周的间隔检查精液质量,血清睾酮和半血浆超氧化物歧化酶(SOD)活性。 泛菌醇改善精子活力,降低形态学异常的精子,并增加精血浆SOD活性; 然而,它对睾酮水平,精液体积和精子数没有影响。 Ubiquinol补充可以用作不育犬的非内分泌治疗。

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