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Effectiveness of interventions based on patient empowerment in the control of type 2 diabetes in sub‐Saharan Africa: A review of randomized controlled trials

机译:基于患者赋予患者赋予亚撒哈拉非洲2型糖尿病的干预措施的有效性:对随机对照试验的综述

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Background It is estimated that 1.6 million deaths worldwide were directly caused by diabetes in 2016, and the burden of diabetes has been increasing rapidly in low‐ and middle‐income countries. This study reviews existing interventions based on patient empowerment and their effectiveness in controlling diabetes in sub‐Saharan Africa. Method PubMed, MEDLINE, EMBASE, CINAHL, Web of Science, PsycINFO and Global Health were searched through August 2018, for randomized controlled trials of educational interventions on adherence to the medication plan and lifestyle changes among adults aged 18?years and over with type 2 diabetes. Random‐effects meta‐analysis was used. Results Eleven publications from nine studies involving 2743 participants met the inclusion criteria. The duration of interventions with group education and individual education ranged from 3 to 12?months. For six studies comprising 1549 participants with meta‐analysable data on glycaemic control (HbA1c), there were statistically significant differences between intervention and control groups: mean difference was ?0.57 [95% confidence interval (CI) ?0.75, ?0.40] ( P ?.00001, I 2 ?=?27%). Seven studies with meta‐analysable data on blood pressure showed statistically significant differences between groups in favour of interventions. Subgroup analyses on glycaemic control showed that long‐term interventions were more effective than short‐term interventions and lifestyle interventions were more effective than diabetes self‐management education. Conclusion This review supports the findings that interventions based on patient empowerment may improve glycaemia (HbA1c) and blood pressure in patients with diabetes. The long‐term and lifestyle interventions appear to be the most effective interventions for glycaemic control.
机译:背景技术据估计,全球160万人死亡直接由2016年糖尿病造成的,糖尿病的负担在低收入和中等收入国家迅速增加。本研究审议了基于患者赋权的现有干预及其在撒哈拉以南非洲糖尿病控制糖尿病的有效性。 2018年8月,研究了PubMed,Medline,Embase,Cinahl,科学网,Psycinfo和全球健康的科学版,用于遵守18岁的成年人和生活方式的依从性的教育干预措施的随机对照试验糖尿病。使用随机效应元分析。结果涉及2743名参与者的9项研究的11个出版物符合纳入标准。群体教育和个人教育的干预措施范围为3至12个月。几个月。对于六项研究,所述研究包括1549名参与者对血糖对照(HBA1C)的血糖调分数据,干预和对照组之间存在统计学显着差异:平均差异是α0.57 [95%置信区间(CI)?0.75,?0.40](P &?。00001,I 2?=?27%)。七项关于血压的血压数据的研究表明,基团之间的统计学显着差异,有利于干预措施。血糖对血糖控制的分析表明,长期干预措施比短期干预措施更有效,生活方式干预比糖尿病自我管理教育更有效。结论,本综述支持基于患者赋权的干预的结果可以改善糖尿病患者的血糖(HBA1C)和血压。长期和生活方式干预似乎是血糖控制最有效的干预措施。

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