Depression's Dance with Inflammation

CARINA STORRS

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Depression's Dance with Inflammation

机译：抑郁与炎症共舞

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Depression can be a devastating illness, plaguing millions of people worldwide with feelings of sadness, hopelessness, apathy and fatigue. Despite numerous antidepressant drugs, as many as a third of patients don't respond to medication. This has forced doctors to be more creative in finding different treatments for the condition. In the past two decades, researchers have tied depression to a seemingly unrelated condition: inflammation, the body's natural response to stress. It could stem from injury or infection, or even emotional issues like an unhappy marriage or problems at work. Some amount of inflammation is generally beneficial, as it ramps up production of cytokines, proteins that help us heal and protect us from the effects of overexertion.

机译：抑郁症可能是毁灭性的疾病，使全世界数以百万计的人感到悲伤，绝望，冷漠和疲劳。尽管有许多抗抑郁药，但仍有多达三分之一的患者对药物没有反应。这迫使医生在寻找针对该病的不同治疗方法方面更具创造力。在过去的二十年中，研究人员将抑郁症与一种看似无关的疾病联系在一起：炎症是人体对压力的自然反应。它可能来自受伤或感染，甚至是感情问题，例如婚姻不快乐或工作中的问题。一定程度的炎症通常是有益的，因为它可以增加细胞因子的生成，这些蛋白可以帮助我们治愈并保护我们免受过度劳累的影响。

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《Discover》 |2014年第6期|2022|共2页
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CARINA STORRS;
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Depression's Dance with Inflammation

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