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Accumulation of c-src mRNA is developmentally regulated in embryonic neural retina.

机译:C-SRC mRNA的积累在胚胎神经视网膜中发育调节。

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Accumulation of c-src mRNA gradually increased during early development of the neural retina in chicken embryos and reached a peak by days 11 to 13 of embryonic life. Thereafter, its amount declined to a low level which persisted also in adult retina. The early increase in c-src mRNA correlated inversely with the decrease in the amount of H3.2 replication histone mRNA and with the decline in the rate of cell growth. The accumulation profile of c-src mRNA corresponded to that of pp60c-src protein, suggesting that the latter is regulated at the level of transcription.
机译:在鸡胚的神经视网膜的早期发育期间C-SRC mRNA的积累逐渐增加,并达到胚胎生命的第11至13天的峰值。此后,其量下降到持续存在于成人视网膜的低水平。 C-SRC mRNA的早期增加与H3.2复制组蛋白mRNA的量的减少相关,并且细胞生长速率下降。 C-SRC mRNA的累积曲线对应于PP60C-SRC蛋白的C-SRC mRNA的累积分布,表明后者在转录水平下调节。

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