Persistent organic pollutants in early pregnancy and risk of gestational diabetes mellitus

Vafeiadi Marina; Roumeliotaki Theano; Chalkiadaki Georgia; Rantakokko Panu; Kiviranta Hannu; Fthenou Eleni; Kyrtopoulos Soterios A.; Kogevinas Manolis; Chatzi Leda

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Persistent organic pollutants in early pregnancy and risk of gestational diabetes mellitus

机译：妊娠早期持久性有机污染物与妊娠糖尿病的风险

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Background: Persistent organic pollutants (POPs) are a group of diverse substances, including polychlorinated biphenyls (PCBs) and organochlorine pesticides that are resistant to biodegradation and ubiquitously present in our environment. Exposure to endocrine disrupting chemicals such as POPs has been linked to type 2 diabetes and metabolic disturbances in epidemiological and animal studies, but little is known about POPs exposure during pregnancy and the development of gestational diabetes mellitus (GDM). The purpose of this study was to determine the extent to which exposure to current low levels of different POPs in the first trimester of pregnancy is associated with GDM risk in 939 women from the "Rhea" pregnancy cohort in Crete, Greece.

机译：背景：持久性有机污染物（POPs）是一类多样的物质，包括多氯联苯（PCBs）和有机氯农药，它们具有抗生物降解作用，并普遍存在于我们的环境中。在流行病学和动物研究中，暴露于内分泌破坏性化学物质（如POPs）已与2型糖尿病和代谢紊乱相关，但对孕妇和妊娠糖尿病（GDM）期间的POPs暴露知之甚少。这项研究的目的是确定希腊克里特岛“ Rhea”妊娠队列中的939名妇女在妊娠前三个月暴露于当前低水平的不同POPs与GDM风险相关的程度。

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来源
《Environment international》 |2017年第1期|89-95|共7页
作者
Vafeiadi Marina; Roumeliotaki Theano; Chalkiadaki Georgia; Rantakokko Panu; Kiviranta Hannu; Fthenou Eleni; Kyrtopoulos Soterios A.; Kogevinas Manolis; Chatzi Leda;
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作者单位

Univ Crete, Fac Med, Dept Social Med, POB 2208, Iraklion 71003, Crete, Greece;

Univ Crete, Fac Med, Dept Social Med, POB 2208, Iraklion 71003, Crete, Greece;

Univ Crete, Fac Med, Dept Social Med, POB 2208, Iraklion 71003, Crete, Greece;

Natl Inst Hlth & Welf, Chem & Hlth Unit, Dept Environm Hlth, Kuopio, Finland;

Natl Inst Hlth & Welf, Chem & Hlth Unit, Dept Environm Hlth, Kuopio, Finland;

Univ Crete, Fac Med, Dept Social Med, POB 2208, Iraklion 71003, Crete, Greece;

Natl Hellen Res Fdn, Inst Biol Med Chem & Biotechnol, Athens, Greece;

Ctr Res Environm Epidemiol CREAL, Barcelona, Spain|Hosp Mar, Res Inst IMIM, Barcelona, Spain|CIBER Epidemiol & Salud Publ CIBERESP, Barcelona, Spain;

Univ Crete, Fac Med, Dept Social Med, POB 2208, Iraklion 71003, Crete, Greece;

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收录信息美国《科学引文索引》(SCI);美国《工程索引》(EI);美国《化学文摘》(CA);
原文格式 PDF
正文语种 eng
中图分类
关键词
Gestational diabetes mellitus; Persistent organic pollutants; Polychlorinated biphenyls (PCBs); Organochlorine pesticides; Pregnancy;

机译：妊娠期糖尿病;持久性有机污染物;多氯联苯;有机氯农药;怀孕;

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机译：与妊娠期糖尿病相关的多个持久性有机污染物组合暴露的有效成分的鉴定及优先序列
2. Association between serum concentrations of persistent organic pollutants and gestational diabetes mellitus in primiparous women [J] . Bita Eslami, Kazem Naddafi, Noushin Rastkari, Environmental research . 2016,第nova期

机译：初产妇血清持久性有机污染物浓度与妊娠糖尿病的相关性
3. Relationship between serum concentrations of persistent organic pollutants and markers of insulin resistance in a cohort of women with a history of gestational diabetes mellitus [J] . Juan P. Arrebola, Amalia Gonzalez-Jimenez, Constanza Fornieles-Gonzalez, Environmental research . 2015,第jana期

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4. A Prediction Model of Gestational Diabetes Mellitus Based on First Pregnancy Test Index [C] . Jianzhuo Yan, Yanan Geng, Hongxia Xu, International Conference on Health Information Science . 2020

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5. Efecto de la Insulinoterapia en el Endotelio Fetoplacentario de Embarazos con Diabetes Mellitus Gestacional =Effect of Insulin Therapy on the Fetoplacental Endothelium of Pregnancies with Gestational Diabetes Mellitus [D] . Subiabre Morales, Mario Enrique. 2020

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6. Pre-Pregnancy Maternal Exposure to Persistent Organic Pollutants and Gestational Weight Gain: A Prospective Cohort Study [O] . Lindsay M. Jaacks, Dana Boyd Barr, Rajeshwari Sundaram, 2016

机译：孕前孕妇持续性有机污染物和妊娠体重增加的前瞻性队列研究
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机译：PrediaBetess和怀孕：怀孕早期HBA1C识别澳大利亚原住民患有高风险的妊娠期糖尿病和不良围产期结果

Persistent organic pollutants in early pregnancy and risk of gestational diabetes mellitus

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