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Lung function growth trajectories in non-asthmatic children aged 4-9 in relation to prenatal exposure to airborne particulate matter and polycyclic aromatic hydrocarbons - Krakow birth cohort study

机译:与产前暴露于空气中的颗粒物和多环芳烃相关的4-9岁非哮喘儿童肺功能增长轨迹-克拉科夫出生队列研究

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摘要

Background: Patterns of lung function development during childhood can be helpful in understanding the pathogenesis of respiratory diseases. A variety of environmental and lifestyle factors, present from the prenatal period to adulthood, may affect or modulate lung function growth. The aim of this study was to investigate, the associations between individual growth trajectories of children's lung function during childhood and prenatal exposure to airborne fine particulate matter (PM2.5) and polycyclic aromatic hydrocarbons (PAH), which were hypothesized to adversely affect spirometry parameters.
机译:背景:儿童时期肺功能的发展模式可能有助于了解呼吸系统疾病的发病机理。从产前到成年,各种环境和生活方式因素都可能影响或调节肺功能的增长。这项研究的目的是调查儿童的肺生长的个体成长轨迹与婴儿暴露于空气中的细颗粒物(PM2.5)和多环芳烃(PAH)的产前暴露之间的关联,这些关联被假设会对肺活量测定参数产生不利影响。

著录项

  • 来源
    《Environmental research》 |2018年第10期|150-157|共8页
  • 作者单位

    Jagiellonian Univ, Dept Epidemiol, Chair Epidemiol & Prevent Med, Med Coll, Kopernika 7a, PL-31034 Krakow, Poland;

    Jagiellonian Univ, Dept Epidemiol, Chair Epidemiol & Prevent Med, Med Coll, Kopernika 7a, PL-31034 Krakow, Poland;

    Jagiellonian Univ, Dept Epidemiol, Chair Epidemiol & Prevent Med, Med Coll, Kopernika 7a, PL-31034 Krakow, Poland;

    Harvard Sch Publ Hlth, Dept Environm Hlth, POB 15677,Landmark 406 West,401 Pk Dr, Boston, MA 02215 USA;

    Southwest Res Inst, Dept Analyt & Environm Chem, 6220 Culebra Rd, San Antonio, TX 78228 USA;

    Jagiellonian Univ, Dept Epidemiol, Chair Epidemiol & Prevent Med, Med Coll, Kopernika 7a, PL-31034 Krakow, Poland;

    Jagiellonian Univ, Dept Epidemiol, Chair Epidemiol & Prevent Med, Med Coll, Kopernika 7a, PL-31034 Krakow, Poland;

    Jagiellonian Univ, Dept Epidemiol, Chair Epidemiol & Prevent Med, Med Coll, Kopernika 7a, PL-31034 Krakow, Poland;

    Columbia Univ, Columbia Ctr Childrens Environm Hlth, Mailman Sch Publ Hlth, 722 West 168 St, New York, NY 10032 USA;

    Columbia Univ, Columbia Ctr Childrens Environm Hlth, Mailman Sch Publ Hlth, 722 West 168 St, New York, NY 10032 USA;

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  • 原文格式 PDF
  • 正文语种 eng
  • 中图分类
  • 关键词

    Krakow cohort; Spirometry parameters; PAH; PM2.5; Trajectory;

    机译:克拉科夫队列;旋光度参数;PAH;PM2.5;轨迹;

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