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首页> 外文期刊>Environmental Science & Technology >Hypoxia Affects Sex Differentiation and Development,Leading to a Male-Dominated Population in Zebrafish (Danio rerio)
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Hypoxia Affects Sex Differentiation and Development,Leading to a Male-Dominated Population in Zebrafish (Danio rerio)

机译：缺氧影响性别分化和发育，导致斑马鱼（Danio rerio）中以男性为主的种群。

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摘要

Hypoxia is affecting thousands of square kilometers of water and has caused declines in fish populations and major changes in aquatic communities worldwide.For the first time,we report that hypoxia can affect sex differentiation and sex development of zebrafish (Danio rerio),leading to a male-biased population in the F1 generation (74.4% +-1.7% males in the hypoxic groups versus 61.9% +-1.6% males in the normoxic groups,n = 5;p < 0.05,x~2 test).The increase in males was associated with downregulations of various genes controlling the synthesis of sex hormones (i.e.,3beta-HSD,CYP11A,CYP19A,and CYP19B)as well as an increase in the testosterone/estradiol ratio.The male-dominated populations caused by hypoxia will have reduced reproductive success,thereby threatening the sustainability of natural fish populations.
机译：缺氧影响了数千平方公里的水，并导致鱼类种群减少和全球水生群落的重大变化。我们首次报道缺氧会影响斑马鱼的性别分化和性发育，导致斑马鱼F1代的男性偏见人群（低氧组男性占74.4％+ -1.7％，而正常氧组中男性占61.9％+ -1.6％，n = 5; p <0.05，x〜2检验）。男性与控制性激素合成的各种基因（即3beta-HSD，CYP11A，CYP19A和CYP19B）的下调以及睾丸激素/雌二醇比的升高有关。低氧引起的男性主导人群将有繁殖成功率下降，从而威胁到天然鱼类种群的可持续性。

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  • 来源
    《Environmental Science & Technology》 |2006年第9期|p.3118-3122|共5页
  • 作者

    EVA H.H.SHANG; RICHARD M.K.YU; RUDOLF S.S.WU;

  • 作者单位

    Centre for Coastal Pollution and Conservation,City University of Hong Kong,83 Tat Chee Avenue,Kowloon,Hong Kong SAR;

    Centre for Coastal Pollution and Conservation,City University of Hong Kong,83 Tat Chee Avenue,Kowloon,Hong Kong SAR;

    Centre for Coastal Pollution and Conservation,City University of Hong Kong,83 Tat Chee Avenue,Kowloon,Hong Kong SAR;

  • 收录信息 美国《科学引文索引》(SCI);美国《工程索引》(EI);美国《生物学医学文摘》(MEDLINE);美国《化学文摘》(CA);
  • 原文格式 PDF
  • 正文语种 eng
  • 中图分类 环境化学;
  • 关键词

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