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首页> 外文期刊>Environmental Science & Technology >Polybrominated diphenyl ethers and polychlorinated biphenyls in human adipose tissue from New York
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Polybrominated diphenyl ethers and polychlorinated biphenyls in human adipose tissue from New York

机译：来自纽约的人脂肪组织中的多溴联苯醚和多氯联苯

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Human adipose tissue samples (n = 52) collected in New York City during 2003-2004 were analyzed for the presence of polybrominated diphenyl ethers (PBDEs) and polychlorinated biphenyls (PCBs). Concentrations of PBDEs in adipose tissues ranged from 17 to 9630 ng/g, lipid wt (median: 77; mean: 399 ng/g, lipid wt; sum all di- through hexa-BDE congeners). Average PBDE concentrations in human adipose tissues from New York City were 10- to 100-times greater than those reported for European countries. A concentration of 9630 ng/g, lipid wt, found in a sample of adipose tissue, is one of the highest concentrations reported to date. PBDE 47 (2,2',4,4'-tetraBDE) was the major congener detected in human tissues, followed by PBDE congeners #99 (2,2',4,4',5-pentalBDE), 100 (2,2',4,4',6-pentaBDE), and 153 (2,2',4,4',5,5'-hexaBDE). A few individuals contained PBDE 153 as the predominant congener in total PBDE concentrations, suggesting alternative exposure sources, possibly occupational. Principal component analysis of PBDE congener composition in human adipose tissues revealed the presence of five clusters, each characterized by varying composition. No significant difference was found in the concentrations of PBDEs between gender. Concentrations of PBDEs were, on average, similar to those for PCBs in human adipose tissues, and substantially higher when PBDE outliers were retained. PBDE and PCB concentrations were not correlated. PBDE concentrations did not increase with increasing age of the subjects, whereas concentrations of PCBs increased with increasing age in males but not in females in this study. These results suggest differences between PBDEs and PCBs in their sources or time course of exposure and disposition. The presence of comparable or greater concentrations of PBDEs, relative to PCBs, highlights the importance of recent voluntary and regulatory efforts to cease production of commercial penta- and octa-BDE in North America, although these efforts do not address continuing emissions from existing sources, such as polyurethane foams.
机译：分析了2003-2004年在纽约市收集的人体脂肪组织样本（n = 52）中是否存在多溴联苯醚（PBDEs）和多氯联苯（PCBs）。脂肪组织中PBDEs的浓度范围为脂质wt（17至9630 ng / g）（中位数：77；平均值：399 ng / g，脂质wt；所有六-BDE同系物的总和）。来自纽约市的人体脂肪组织中的多溴二苯醚平均浓度比欧洲国家报告的平均浓度高10至100倍。在脂肪组织样品中发现的9630 ng / g脂质重量浓度是迄今为止报道的最高浓度之一。 PBDE 47（2,2'，4,4'-tetraBDE）是在人体组织中检测到的主要同源物，其次是PBDE同源物＃99（2,2'，4,4'，5-pentalBDE），100（2， 2'，4,4'，6-pentaBDE）和153（2,2'，4,4'，5,5'-hexaBDE）。少数人在多溴二苯醚总浓度中以多溴二苯醚153为主要同源物，表明有其他接触源，可能是职业接触源。对人脂肪组织中多溴二苯醚同源物成分的主成分分析显示，存在五个簇，每个簇的特征均在于组成不同。性别之间的多溴二苯醚浓度没有发现显着差异。平均而言，PBDEs的浓度与人体脂肪组织中PCBs的浓度相似，而当保留PBDE离群值时，PBDEs的浓度则明显更高。 PBDE与PCB浓度无关。在该研究中，PBDE的浓度并没有随着受试者年龄的增加而增加，而PCB的浓度随男性的增加而增加，而女性没有。这些结果表明，多溴二苯醚和多氯联苯的来源或暴露和处置的时间过程存在差异。相对于多氯联苯，存在相当或更高浓度的多溴二苯醚，这凸显了最近的自愿和监管努力对于在北美停止生产商用五溴二苯醚和八溴二苯醚的重要性，尽管这些努力并未解决现有来源不断产生的排放问题，例如聚氨酯泡沫。

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