...
  • 主题
高级搜索  >
历史搜索 清空历史
首页> 外文期刊>European Journal of Applied Physiology >The effect of 4 weeks β-alanine supplementation and isokinetic training on carnosine concentrations in type I and II human skeletal muscle fibres
【24h】

The effect of 4 weeks β-alanine supplementation and isokinetic training on carnosine concentrations in type I and II human skeletal muscle fibres

机译：补充4周β丙氨酸和等速运动训练对I型和II型人骨骼肌纤维肌肽浓度的影响

获取原文
获取原文并翻译 | 示例
           
页面导航
  • 摘要
  • 著录项
  • 相似文献
  • 相关主题

摘要

Seven male students were supplemented with β-alanine (β-ALG) for 4 weeks (6.4 g day?1) and seven with a matching placebo (PLG). Subjects undertook 4 weeks of isokinetic training with the right leg (T) whilst the left leg was untrained (UT), serving as a control. Each training session consisted of 10 × 10 maximal 90° extension and flexion contractions at 180°/s using a Kin-Com isokinetic dynamometer, with 1 min rest between bouts. Muscle biopsies were taken from the vastus lateralis immediately before and at the end of the supplementation period. Following freeze drying muscle fibres were dissected and characterised by their MHC profile, as type I, IIa, IIx, or as hybrids of these. Carnosine was measured by HPLC. There was a significant increase in carnosine in both T and UT legs of the β-ALG (9.63 ± 3.92 mmol kg?1 dry muscle and 6.55 ± 2.36 mmol kg?1 dry muscle respectively). There was a significant increase in the carnosine content of all fibre phentotypes, with no significant difference between types. There were no significant differences in the changes in muscle or in fibres between the T and UT legs. In contrast there was no significant change in the carnosine content in either the T or UT legs with placebo. The results indicate that 4 weeks training has no effect on the muscle carnosine content. Whilst an increase was seen with β-alanine supplementation, this was not further influenced by training. These findings suggest that β-alanine availability is the main factor regulating muscle carnosine synthesis.
机译：7名男学生补充了4周（6.4 g day？1 ）的β-丙氨酸（β-ALG），另外7名则补充了匹配的安慰剂（PLG）。受试者用右腿（T）进行了4周的等速运动训练，而未训练的左腿（UT）作为对照。每次训练均由Kin-Com等速测功机在180°/ s下进行10×10最大90°伸展和屈曲收缩，每回合之间休息1分钟。在补充期之前和结束时从外侧股肌取活检。冷冻干燥后，解剖肌肉纤维，并通过其MHC谱（I型，IIa型，IIx型或它们的杂种）进行表征。肌肽通过HPLC测量。 β-ALG的T和UT腿的肌肽含量均显着增加（分别为9.63±3.92 mmol kg？1 干肌和6.55±2.36 mmol kg？1 干肌）。所有纤维表型的肌肽含量均显着增加，各类型之间无显着差异。 T和UT腿之间的肌肉或纤维变化无明显差异。相比之下，使用安慰剂的T腿或UT腿的肌苷含量没有明显变化。结果表明，训练4周对肌肉肌肽含量没有影响。虽然补充β-丙氨酸的增加，但不受训练的进一步影响。这些发现表明，β-丙氨酸的可用性是调节肌肉肌肽合成的主要因素。

著录项

相似文献

  • 外文文献
  • 中文文献
  • 专利
获取原文

客服邮箱：kefu@zhangqiaokeyan.com

京公网安备：11010802029741号 ICP备案号：京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有

  • 客服微信

  • 服务号