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Bacterial composition of respiratory organs and intestine in Mice and Rats

机译：小鼠和大鼠呼吸器官和肠道的细菌组成

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Bacterial pathogens in laboratory animals such as mice and rats have been highlighted, since those microorganisms can affect the experiment data by causing side immune responses. Relatively, the bacterial composition of each organ in mice and rats was not an interesting issue. In this study, the bacterial composition of respiratory organs and intestine were monitored from 247 mice and 200 rats in Korea by biochemical properties and 16S rDNA sequencing. 1,279 isolates in total were identified, and classified to 35 species of 17 genera. In case of rats, E. coli, P. mirabilis, M. morganii, C. freundii, and P. vulgaris were prevalent in gut, and E. coli, P. mirabilis, S. aureus, S. cohnii, and M morganii were dominant in respiratory organs. In mice, E. coli, P. mirabilis, A. Iwoffi, and L. adecarboxylata were prevalent in intestines, but in respiratory organs, E. coli, B. sphaericus, S. auricularis, A. Iwoffi, and L. adecarboxylata were dominant. B. sphaericus, G morbillorum, S. paucimobilis, Staphylococcus spp. were specific in respiratory organs, and M. morganii and Citrobacter spp. were more prevalent in intestine than in respiratory organs.
机译：实验动物（如小鼠和大鼠）中的细菌病原体已被重点研究，因为这些微生物可通过引起副免疫反应而影响实验数据。相对而言，小鼠和大鼠中每个器官的细菌组成并不是一个有趣的问题。在这项研究中，通过生化特性和16S rDNA测序监测了韩国247只小鼠和200只大鼠的呼吸器官和肠道细菌组成。共鉴定出1279株，并归类到17属35种。在大鼠的情况下，肠道中普遍存在大肠埃希氏菌，奇异疟原虫，摩根支原体，弗氏梭状芽胞杆菌和寻常性支原体，而大肠杆菌，奇异菌，金黄色葡萄球菌，co.ii和摩氏支原体在呼吸器官中占主导地位。在小鼠中，大肠埃希氏菌，奇异疟原虫，A。Iwoffi和L. adecarboxylata普遍存在，但在呼吸器官中，大肠杆菌，球形芽孢杆菌，A。Iuroffis，A。Iwoffi和L. adecarboxylata普遍存在。优势。球形芽孢杆菌，G morbillorum，短孢菌，葡萄球菌属。特异于呼吸器官，以及摩根分枝杆菌和柠檬酸杆菌属。在肠道中比在呼吸器官中更普遍。

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