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Seasonal influence on phenolic-mediated antihyperglycemic properties of Canadian sugar and red maple leaves using in vitro assay models

机译:使用体外测定模型对加拿大糖和红枫叶的酚介导的降血糖特性的季节性影响

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摘要

Red and sugar maple leaves collected in the summer and fall from Canada, were evaluated for phenolic content, antioxidant, α-glucosidase, and α-amylase inhibitory activities variation. The phenolic contents of summer red maple leaves (RML-S) and summer sugar maple leaves (SML-S) were higher than red and sugar maple leaves collected in fall (RML-F and SML-F, respectively). HPLC analyses showed differences in phenolic compounds present in the SML samples compared to the RML samples. The extracts were assayed for yeast and rat α-glucosidase inhibitory activities. Both results showed that SML-S extracts had the highest inhibitory activity which could possibly be attributed to the unique phenolics present therein. Milder effects were observed in terms of α-amylase inhibitory activity, with RML-F having the highest inhibitory activity. These results suggest that maple tree leaf extracts may have potential for phenolic-mediated α-glucosidase inhibition, relevant to type 2 diabetes management, with SML-S extract having the highest bioactivity.
机译:评估了从加拿大夏季和秋季采集的红枫糖枫糖叶的酚含量,抗氧化剂,α-葡萄糖苷酶和α-淀粉酶抑制活性的变化。夏季红枫叶(RML-S)和夏季糖枫叶(SML-S)的酚含量高于秋季采集的红枫糖枫糖(分别为RML-F和SML-F)。 HPLC分析显示,与RML样品相比,SML样品中存在的酚类化合物有所不同。分析提取物的酵母和大鼠α-葡萄糖苷酶抑制活性。两项结果均表明,SML-S提取物具有最高的抑制活性,这可能归因于其中存在的独特酚类。在α-淀粉酶抑制活性方面观察到较弱的作用,其中RML-F具有最高的抑制活性。这些结果表明,枫叶提取物可能具有酚介导的α-葡萄糖苷酶抑制作用,与​​2型糖尿病的治疗有关,而SML-S提取物具有最高的生物活性。

著录项

  • 来源
    《Food Science and Biotechnology》 |2012年第3期|p.753-760|共8页
  • 作者单位

    Department of Chemistry and Food Science, Framingham State University, Framingham, MA, 01701, USA;

    Bioactive Botanical Research Laboratory, Department of Biomedical and Pharmaceutical Science, University of Rhode Island, Kingston, RI, 02881, USA;

    Department of Nutrition and Food Sciences, Food Science and Nutrition Research Center, West Kingston, RI, 02892, USA;

    Department of Nutrition and Food Sciences, Food Science and Nutrition Research Center, West Kingston, RI, 02892, USA;

    Bioactive Botanical Research Laboratory, Department of Biomedical and Pharmaceutical Science, University of Rhode Island, Kingston, RI, 02881, USA;

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  • 原文格式 PDF
  • 正文语种 eng
  • 中图分类
  • 关键词

    sugar maple; red maple; phenolic profile; α-amylase; α-glucosidase;

    机译:糖枫;红枫;酚类;α-淀粉酶;α-葡萄糖苷酶;

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