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Synthesizing results of multiple randomized experiments to establish causality in mediation testing

机译：综合多个随机实验的结果以建立调解测试的因果关系

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摘要

Mediation has to do with the transfer of causality from an independent variable to a dependent variable via a third variable called a "mediator." Because the experimental method is the universally recognized gold standard for establishing causality, we propose that conducting two experiments, one manipulating the independent variable and another manipulating the hypothesized mediator, most rigorously tests mediation hypotheses. When there are several experiments in which the independent variable was manipulated and also several experiments in which the mediator was manipulated, synthesizing these two sets of experiments using meta-analysis yields the ultimate mediation evidence. If these experiments were conducted in the field, both internal validity and external validity would be maximized. An example of the synthesis of multi-experiment mediation tests is provided and its potential and limitations are discussed. (C) 2015 Elsevier Inc. All rights reserved.
机译：调解与因果关系通过一个称为“调解人”的第三个变量从自变量到因变量的传递有关。因为实验方法是建立因果关系的公认标准，所以我们建议进行两个实验，一个是操纵自变量，另一个是操纵假设的中介者，最严格地测试中介假设。当有多个使用自变量的实验以及多个使用介体的实验时，使用荟萃分析综合这两套实验可得出最终的中介证据。如果在现场进行这些实验，则内部有效性和外部有效性都将得到最大化。提供了综合实验调解测试的示例，并讨论了其潜力和局限性。 （C）2015 Elsevier Inc.保留所有权利。

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