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首页> 外文期刊>Medical Imaging, IEEE Transactions on >Comb-Push Ultrasound Shear Elastography (CUSE): A Novel Method for Two-Dimensional Shear Elasticity Imaging of Soft Tissues
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Comb-Push Ultrasound Shear Elastography (CUSE): A Novel Method for Two-Dimensional Shear Elasticity Imaging of Soft Tissues

机译：梳推式超声剪切弹性成像（CUSE）：一种用于软组织的二维剪切弹性成像的新方法

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摘要

Fast and accurate tissue elasticity imaging is essential in studying dynamic tissue mechanical properties. Various ultrasound shear elasticity imaging techniques have been developed in the last two decades. However, to reconstruct a full field-of-view 2-D shear elasticity map, multiple data acquisitions are typically required. In this paper, a novel shear elasticity imaging technique, comb-push ultrasound shear elastography (CUSE), is introduced in which only one rapid data acquisition (less than 35 ms) is needed to reconstruct a full field-of-view 2-D shear wave speed map (40$,times ,$38 mm). Multiple unfocused ultrasound beams arranged in a comb pattern (comb-push) are used to generate shear waves. A directional filter is then applied upon the shear wave field to extract the left-to-right (LR) and right-to-left (RL) propagating shear waves. Local shear wave speed is recovered using a time-of-flight method based on both LR and RL waves. Finally, a 2-D shear wave speed map is reconstructed by combining the LR and RL speed maps. Smooth and accurate shear wave speed maps are reconstructed using the proposed CUSE method in two calibrated homogeneous phantoms with different moduli. Inclusion phantom experiments demonstrate that CUSE is capable of providing good contrast (contrast-to-noise ratio $ ge $ 25 dB) between the inclusion and background without artifacts and is insensitive to inclusion positions. Safety measurements demonstrate that all regulated parameters of the ultrasound output level used in CUSE sequence are well below the FDA limits for diagnostic ultrasound.
机译：快速而准确的组织弹性成像对于研究动态组织力学性能至关重要。在最近的二十年中，已经开发了各种超声剪切弹性成像技术。但是，为了重建完整的视场二维剪切弹性图，通常需要进行多次数据采集。在本文中，介绍了一种新颖的剪切弹性成像技术，即梳状超声剪切弹性成像技术（CUSE），该技术仅需要一次快速数据采集（少于35 ms）即可重建全视场二维横波速度图（40 $，times，$ 38 mm）。排列成梳状（梳状）的多个未聚焦超声束用于产生剪切波。然后将方向滤波器应用于剪切波场，以提取从左向右（LR）和从右向左（RL）传播的剪切波。使用基于LR和RL波的飞行时间方法恢复局部剪切波速度。最后，通过组合LR和RL速度图来重建二维剪切波速度图。使用建议的CUSE方法在两个具有不同模量的经过校准的均质体模上，重建了平滑准确的横波速度图。夹杂物模型实验表明，CUSE能够在夹杂物和背景之间提供良好的对比度（对比度噪声比$ ge $ 25 dB），并且没有伪影，并且对夹杂物位置不敏感。安全性测量表明，CUSE序列中使用的所有超声输出水平调节参数均远低于FDA诊断超声的限值。

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