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首页> 外文期刊>IEEE Transactions on Ultrasonics, Ferroelectrics, and Frequency Control >Intracardiac acoustic radiation force impulse (ARFI) and shear wave imaging in pigs with focal infarctions
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Intracardiac acoustic radiation force impulse (ARFI) and shear wave imaging in pigs with focal infarctions

机译：局灶性梗死猪的心内声辐射力脉冲（ARFI）和切波成像

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摘要

Four pigs, three with focal infarctions in the apical intraventricular septum (IVS) and/or left ventricular free wall (LVFW), were imaged with an intracardiac echocardiography (ICE) transducer. Custom beam sequences were used to excite the myocardium with focused acoustic radiation force (ARF) impulses and image the subsequent tissue response. Tissue displacement in response to the ARF excitation was calculated with a phase-based estimator, and transverse wave magnitude and velocity were each estimated at every depth. The excitation sequence was repeated rapidly, either in the same location to generate 40 Hz M-modes at a single steering angle, or with a modulated steering angle to synthesize 2-D displacement magnitude and shear wave velocity images at 17 points in the cardiac cycle. Both types of images were acquired from various views in the right and left ventricles, in and out of infarcted regions. In all animals, acoustic radiation force impulse (ARFI) and shear wave elasticity imaging (SWEI) estimates indicated diastolic relaxation and systolic contraction in noninfarcted tissues. The M-mode sequences showed high beat-to-beat spatio-temporal repeatability of the measurements for each imaging plane. In views of noninfarcted tissue in the diseased animals, no significant elastic remodeling was indicated when compared with the control. Where available, views of infarcted tissue were compared with similar views from the control animal. In views of the LVFW, the infarcted tissue presented as stiff and non-contractile compared with the control. In a view of the IVS, no significant difference was seen between infarcted and healthy tissue, whereas in another view, a heterogeneous infarction was seen to be presenting itself as non-contractile in systole.
机译：用心内超声心动图（ICE）传感器对四只猪（三只在心尖室间隔（IVS）和/或左心室游离壁（LVFW）处有梗死灶）成像。使用自定义束序列以聚焦的声辐射力（ARF）脉冲激发心肌，并对随后的组织反应成像。使用基于相位的估计器计算响应ARF激发的组织位移，并在每个深度分别估计横向波的大小和速度。快速重复激励序列，在同一位置以单个转向角生成40 Hz M模式，或者以调制转向角合成心动周期中17个点的二维位移幅度和剪切波速度图像。两种类型的图像都是从右心室和左心室，梗塞区域内外的各种视图获取的。在所有动物中，声辐射力脉冲（ARFI）和剪切波弹性成像（SWEI）估计值表明非梗死组织的舒张期舒张和收缩期收缩。 M模式序列显示出每个成像平面的测量具有较高的逐拍时空重复性。从患病动物的非梗塞组织的观点来看，与对照相比，没有显示出明显的弹性重塑。将梗死组织的视野与对照动物的相似视野进行比较。从LVFW的观点来看，与对照相比，梗塞的组织表现为僵硬且无收缩。从IVS的角度来看，在梗死的组织和健康的组织之间没有发现显着差异，而在另一种观点中，异源性的梗塞被认为在收缩期表现为非收缩性。

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