Tissue stiffness imaging method using temporal variation of ultrasound speckle pattern

Mok-Kun Jeong; Sung-Jae Kwon

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Tissue stiffness imaging method using temporal variation of ultrasound speckle pattern

机译：利用超声散斑图随时间变化的组织刚度成像方法

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Applying vibration to a medium makes it vibrate. The resulting change in scatterer distribution inside the medium due to applied vibration changes the speckle pattern of ultrasound images. In this case, scatterers in a hard medium experience small displacements, and those in a soft medium experience large displacements. As a result, the amount of speckle pattern brightness change in ultrasound images is related to the tissue stiffness. Using this dependency, a two-dimensional profile of relative tissue stiffness can be constructed qualitatively at the display pixel resolution by determining at each pixel the standard deviation and/or the difference between minimum and maximum values over a certain number of consecutive B-mode images. Experiments with phantoms show that the softer the tissue, the larger the standard deviation. The proposed imaging modality is a simple yet practical method of resolving hard cysts surrounded by soft background in a phantom using B-mode frame data only.

机译：对介质施加振动使其振动。由于施加的振动导致的介质内部散射体分布的最终变化会改变超声图像的斑点图案。在这种情况下，硬介质中的散射体位移较小，软介质中的散射体位移较大。结果，超声图像中的斑点图案亮度变化量与组织刚度有关。利用这种依赖性，可以通过在每个像素上确定一定数量的连续B模式图像上的标准偏差和/或最小值和最大值之间的差，在显示像素分辨率下定性地构造相对组织刚度的二维轮廓。。体模实验表明，组织越软，标准偏差越大。提出的成像方式是仅使用B模式帧数据解决幻影中被软背景包围的硬囊肿的简单而实用的方法。

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《IEEE Transactions on Ultrasonics, Ferroelectrics, and Frequency Control》 |2003年第4期|p.457-460|共4页
作者
Mok-Kun Jeong; Sung-Jae Kwon;
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正文语种 eng
中图分类声学工程;计量学;
关键词
biological tissues; biomedical ultrasonics; brightness; speckle; ultrasonic imaging; 2D profile; B-mode images; US imaging; hard cysts; imaging modality; scatterer distribution; speckle pattern brightness variation; temporal variation; tissue stiffness imaging method;

机译：生物组织;生物医学超声;亮度;斑点;超声波成像;2D轮廓;B型图像;US成像;硬囊肿;成像方式;散射体分布;斑点图案亮度变化;时间变化;组织刚度成像方法;

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专利

1. Basic studies on optical imaging of biological tissues using optical speckle patterns modulated by ultrasound [J] . Kazuaki Nakamura, Masataka Kitama, Kenji Misawa, 北海道工業大学研究紀要 . 2002,第30期

机译：利用超声调制的光斑图案对生物组织进行光学成像的基础研究
2. Basic studies on optical imaging of biological tissues using optical speckle patterns modulated by ultrasound [J] . Kazuaki Nakamura, Masataka Kitama, Kenji Misawa, 北海道工業大学研究紀要 . 2002,第30期

机译：超声波调节光学斑点图案的生物组织光学成像的基本研究
3. Quantification of the effects of time-varying speckle patterns on speckle images using a modified speckle influence degree method [J] . Optics Communications: A Journal Devoted to the Rapid Publication of Short Contributions in the Field of Optics and Interaction of Light with Matter . 2020,第期

机译：使用改进的散斑影响度法定量时变散斑图案的斑块效果
4. Tissue stiffness measurement using temporal variation of ultrasound speckle pattern [C] . Mok-Kun Jeong, Jeong-Man Park, Sung-Jae Kwon, Ultrasonic Imaging and Signal Processing . 2003

机译：利用超声散斑图的时间变化测量组织刚度
5. Free of speckle ultrasound images of small tissue structures. [D] . Driscoll, Diana Ivona. 2001

机译：没有小组织结构的斑点超声图像。
6. Monitoring microvascular perfusion variations with laser speckle contrast imaging using a view-based temporal template method [O] . Mohammad Zaheer Ansari, Eun-Jeung Kang, Mioara D. Manole, -1

机译：使用基于视图的时间模板方法通过激光散斑对比成像监测微血管灌注变化
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Tissue stiffness imaging method using temporal variation of ultrasound speckle pattern

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