Noninvasive real-time multipoint temperature control for ultrasoundphased array treatments

Seip R.; VanBaren P.; Cain C.A.; Ebbini E.S.

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Noninvasive real-time multipoint temperature control for ultrasoundphased array treatments

机译：用于超声相控阵治疗的无创实时多点温度控制

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A method for noninvasively estimating spatiotemporal temperaturenchanges in samples using diagnostic ultrasound, and using these asninputs to a multipoint ultrasound phased array temperature controller,nis presented in this paper. This method is based on a linearnrelationship between the apparent tissue echo pattern displacements andntemperature, as seen along A-lines acquired with diagnostic ultrasoundnwhen the sample is heated by external heating fields. Thenproportionality constant between echo displacement and temperature isndetermined by the local change in speed of sound due to temperature andnthe linear coefficient of thermal expansion of the material. Accuratenestimation of the displacements and proportionality constant yieldsnaccurate calibrated high-resolution (1 mm spatial, sub-°C)nnoninvasive sample temperature estimates. These are used as inputs to anmultipoint temperature controller, capable of controlling ultrasoundnphased array treatments in real-time. Phantom and in vitro results shownthat the noninvasively estimated temperature values can effectively benused to control ultrasound hyperthermia treatments, almost replacingninvasive thermocouple measurements. The mathematical background andnassumptions of the noninvasive temperature estimator and the controllernare presented in this paper, together with experimental results showingnestimator and controller performance and limitations. To the best of ournknowledge, this paper presents the first demonstration of real-timentreatment control based entirely on noninvasive temperature estimates

机译：本文介绍了一种使用诊断超声无创地估计样品中时空温度变化的方法，并将这些输入用于多点超声相控阵温度控制器。该方法基于表观组织回波模式位移和温度之间的线性关系，当样品被外部加热场加热时，沿着诊断超声波获取的A线可看到。然后由温度和材料的热膨胀线性系数引起的声速局部变化确定回声位移与温度之间的比例常数。位移的精确估计和比例常数可准确校准高分辨率（1 mm空间，低于°C）的非侵入性样品温度估算值。这些用作多点温度控制器的输入，该控制器能够实时控制超声相控阵治疗。幻像和体外结果表明，可以有效地利用无创估计的温度值来控制超声热疗治疗，几乎替代了无创热电偶测量。本文介绍了无创温度估算器和控制器的数学背景和假设，以及实验结果表明了估算器和控制器的性能和局限性。尽我们所知，本文提出了完全基于无创温度估算的实时治疗控制的首次演示

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《IEEE Transactions on Ultrasonics, Ferroelectrics, and Frequency Control》 |1996年第6期|p.1063-1073|共11页
作者
Seip R.; VanBaren P.; Cain C.A.; Ebbini E.S.;
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正文语种 eng
中图分类声学工程;计量学;
关键词
biomedical ultrasonics; hyperthermia; patient treatment; radiation therapy; temperature control; ultrasonic arrays; A-line; controller; diagnostic ultrasound; estimator; heating field; noninvasive real-time multipoint temperature control; sound speed; thermal expansi;

机译：生物医学超声;高温;病人治疗;放射治疗;温度控制;超声阵列;A线;控制器;诊断超声;估计器;加热场;无创实时多点温度控制;声速;热膨胀;

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专利

1. Noninvasive real-time multipoint temperature control for ultrasound phased array treatments [J] . Seip R., VanBaren P. IEEE Transactions on Ultrasonics, Ferroelectrics, and Frequency Control . 1996,第6期

机译：用于超声相控阵治疗的无创实时多点温度控制
2. Multipoint temperature control during hyperthermia treatments: theory and simulation [J] . VanBaren P., Ebbini E.S. IEEE Transactions on Biomedical Engineering . 1995,第8期

机译：热疗中的多点温度控制：理论与模拟
3. Multipoint temperature control during hyperthermia treatments: theory and simulation [J] . VanBaren P., Ebbini E.S. IEEE Transactions on Biomedical Engineering . 1995,第8期

机译：热疗中的多点温度控制：理论与模拟
4. FEEDBACK CONTROL OF TEMPERATURES DURING HYPERTHERMIA TREATMENTS WITH PHASED-ARRAY ULTRASOUND APPLICATORS [C] . P. VanBaren, E. Beck, E.S. Ebbini, 1995 IEEE engineering in medicine and biology 17th annual conference and 21st Canadian medical and biological engineering conference . 1997

机译：相控阵超声施加器在高温治疗过程中的温度反馈控制
5. Multipoint temperature control. [D] . Borundia, Ajit. 2004

机译：多点温度控制。
6. Multipoint Temperature Monitoring of Microwave Thermal Ablation in Bones through Fiber Bragg Grating Sensor Arrays [O] . Elena De Vita, Martina Zaltieri, Francesca De Tommasi, 2020

机译：通过光纤布拉格光栅传感器阵列对骨骼中微波热消融的多点温度监测
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Noninvasive real-time multipoint temperature control for ultrasoundphased array treatments

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