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首页> 外文期刊>IEEE Transactions on Ultrasonics, Ferroelectrics, and Frequency Control >Noninvasive surgery of prostate tissue by high-intensity focused ultrasound
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Noninvasive surgery of prostate tissue by high-intensity focused ultrasound

机译：高强度聚焦超声的前列腺组织无创手术

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Modern ultrasound transducer material and matching layer technology has permitted us to combine the ultrasound visualization capability with production of high-intensity focused ultrasound (HIFU) on the same ceramic crystal. This development has lead to the design of a transrectal probe for noninvasive surgery of prostate tissue by HIFU. The combined capability using the same ceramic crystal simplifies treatment planning, targeting, and monitoring of tissue before and during the HIFU treatment. This mechanically scanning transrectal probe was introduced for clinical use in 1992 for noninvasive surgery of the prostate to treat benign prostatic hyperplasia (BPH) condition. This paper reviews major steps progressing from conception to the present clinical trial status of the HIFU device. During these clinical studies generation of microbubbles and cavitation were observed. Data from microbubble generation, temperature monitoring in tissue, and autopsy of HIFU-treated animal prostates are presented. Results of human clinical studies are briefly summarized to indicate performance of the device.
机译：现代超声换能器材料和匹配层技术使我们能够将超声可视化功能与在同一陶瓷晶体上产生的高强度聚焦超声（HIFU）相结合。这种发展已导致设计用于HIFU的前列腺组织的非侵入性手术的经直肠探针。使用相同陶瓷晶体的综合功能简化了HIFU治疗之前和期间的治疗计划，目标确定和组织监测。这种机械扫描的经直肠探针于1992年投入临床，用于前列腺的非侵入性手术，以治疗前列腺增生（BPH）状况。本文回顾了从概念到HIFU设备目前的临床试验状态的主要步骤。在这些临床研究过程中，观察到微泡和空化的产生。呈现了来自微气泡产生，组织中的温度监测以及HIFU治疗的动物前列腺的尸检数据。简要总结了人类临床研究结果以表明该设备的性能。

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