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Acute disseminated encephalomyelitis

机译:急性播散性脑脊髓炎

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摘要

The authors report 6 children with the diagnosis of acute disseminated encephalomyelitis. Diagnosis was based on clinical and radiological findings. The most common presenting symptoms were fever and disturbed consciousness, followed by cranial nerve abnormalities and pyramidal signs. Brain MRI showed hyperintense signals on T2-weighted images, most commonly in the subcortical and periventricular white matter, brainstem, basal ganglia and thalamus. The lesions were bilateral, asymmetrical and highly variable in size and number. A preceding infection was present in 3 of 6 children. Early high-dose corticosteroids were given to all the patients. All patients recovered clinically. Follow-up ranged from 10 months to 2 years. No relapses were observed during this period. Early high-dose steroid therapy seems to be an effective treatment in acute disseminated encephalomyelitis.
机译:作者报告了6例诊断为急性播散性脑脊髓炎的儿童。诊断基于临床和放射学发现。最常见的症状是发烧和意识障碍,其次是颅神经异常和锥体束征。脑MRI在T2加权图像上显示高强度信号,最常见于皮层下和脑室周围白质,脑干,基底神经节和丘脑。病变是双侧的,不对称的,在大小和数量上变化很大。 6名儿童中有3名存在先前的感染。所有患者均接受早期大剂量糖皮质激素治疗。所有患者均临床康复。随访时间为10个月至2年。在此期间未观察到复发。早期大剂量类固醇治疗似乎是急性弥漫性脑脊髓炎的有效治疗方法。

著录项

  • 来源
    《Indian Journal of Pediatrics》 |2004年第11期|1035-1038|共4页
  • 作者单位

    Pediatric Intensive Care Unit (PICU), Department of Pediatrics, Lokmanya Tilak Medical College & General Hospital, Sion, Mumbai, India;

    Pediatric Intensive Care Unit (PICU), Department of Pediatrics, Lokmanya Tilak Medical College & General Hospital, Sion, Mumbai, India;

    Pediatric Intensive Care Unit (PICU), Department of Pediatrics, Lokmanya Tilak Medical College & General Hospital, Sion, Mumbai, India;

    Pediatric Intensive Care Unit (PICU), Department of Pediatrics, Lokmanya Tilak Medical College & General Hospital, Sion, Mumbai, India;

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  • 原文格式 PDF
  • 正文语种 eng
  • 中图分类
  • 关键词

    Acute disseminated encephalomyelitis; High dose steroids;

    机译:急性播散性脑脊髓炎;高剂量类固醇;

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