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An efficient parallel numerical modeling of bioheat transfer in realistic tissue structure

机译:逼真的组织结构中生物传热的有效并行数值建模

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摘要

A fast and accurate numerical method of solving bioheat transfer problems is critical for many biomedical applications, such as efficient implementation of thermal therapy planning in a clinical setup, and evaluation of the thermal effects induced by specific energy absorption rate (SAR) from external electromagnetic field. This paper developed a parallel finite-difference method based on alternating direction explicit (ADE) scheme to solve three dimensional transient bioheat equation for the realistic tissue structure. An optimized processing pipeline for accurate presentation of the irregular boundary condition was established to considerably reduce the staircase errors induced by cubic voxel. The voxels order aligned along diagonal direction was designed to allow fast parallel strategy for the lower and upper matrix solution involved in ADE scheme for irregular tissue. The test cases including a real head model have indicated that the developed method can support large time step and cubic voxel approximation of irregular interface and boundary, and also produce significant parallel efficiency.
机译:快速准确的数值方法解决生物热传递问题对于许多生物医学应用至关重要,例如在临床环境中有效实施热疗计划以及评估外部电磁场的比能量吸收率(SAR)引起的热效应。本文开发了一种基于交替方向显式(ADE)方案的并行有限差分方法,用于求解逼真的组织结构的三维瞬态生物热方程。建立了用于精确表示不规则边界条件的优化处理流水线,以显着减少立方体素引起的阶梯误差。沿对角线方向排列的体素顺序被设计为针对不规则组织的ADE方案中涉及的上下矩阵解决方案允许快速并行策略。包含真实头部模型的测试案例表明,所开发的方法可以支持较大的时间步长和不规则界面和边界的立方体素逼近,并且还可以产生显着的并行效率。

著录项

  • 来源
  • 作者

    Zhi-Zhu He; Jing Liu;

  • 作者单位

    Key Laboratory of Cryogenics, and Beijing Key Laboratory of Cryo-Biomedical Engineering, Technical Institute of Physics and Chemistry, Chinese Academy of Sciences, Beijing 100190, China,Technical Institute of Physics and Chemistry, Chinese Academy of Sciences, P.O. Box 2711, Beijing 100190, China;

    Key Laboratory of Cryogenics, and Beijing Key Laboratory of Cryo-Biomedical Engineering, Technical Institute of Physics and Chemistry, Chinese Academy of Sciences, Beijing 100190, China,Department of Biomedical Engineering, School of Medicine, Tsinghua University, Beijing 100084, China;

  • 收录信息 美国《科学引文索引》(SCI);美国《工程索引》(EI);
  • 原文格式 PDF
  • 正文语种 eng
  • 中图分类
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